337924-65-9 Usage
General Description
METHYL 2-(4-CHLOROPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE is a chemical compound that belongs to the class of thiazole carboxylates. It consists of a methyl group attached to a thiazole ring with a carboxylate group at the 5-position and a 4-chlorophenyl group at the 2-position. METHYL 2-(4-CHLOROPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE has potential applications in the field of pharmaceuticals, agrochemicals, and material science due to its unique structure and properties. It may be used in the synthesis of various biologically active compounds and could also be a valuable building block for the development of new drugs and agrochemical agents. Additionally, it may have potential uses in the development of new materials with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 337924-65-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,7,9,2 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 337924-65:
(8*3)+(7*3)+(6*7)+(5*9)+(4*2)+(3*4)+(2*6)+(1*5)=169
169 % 10 = 9
So 337924-65-9 is a valid CAS Registry Number.
337924-65-9Relevant articles and documents
Design, synthesis, and biological evaluation of antiviral agents targeting flavivirus envelope proteins
Li, Ze,Khaliq, Mansoora,Zhou, Zhigang,Post, Carol Beth,Kuhn, Richard J.,Cushman, Mark
experimental part, p. 4660 - 4671 (2009/07/11)
Flavivirus envelope proteins (E proteins) have been shown to play a pivotal role in virus assembly, morphogenesis, and infection of host cells. Inhibition of flavivirus infection of a host cell by means of a small molecule envelope protein antagonist is an attractive strategy for the development of antiviral agents. Virtual screening of the NCI chemical database using the dengue virus envelope protein structure revealed several hypothetical hit compounds. Bioassay results identified a class of thiazole compounds with antiviral potency in cell-based assays. Modification of these lead compounds led to a series of analogues with improved antiviral activity and decreased cytotoxicity. The most active compounds 11 and 36 were effective in the low micromolar concentration range in a cellular assay system.
