33837-93-3Relevant articles and documents
A short and efficient total synthesis of the bromotyrosine-derived alkaloid psammaplysene A
Xu, Jingjing,Wang, Kai,Wu, Jinlong
, p. 13747 - 13749 (2018)
Psammaplysene A, an inhibitor of FOXO1a-mediated nuclear export, has been synthesized by a concise and improved route from tyrosine-derived acid and amine fragments which were easily constructed using commercially available p-hydroxybenzaldehyde and tyramine as starting material, respectively. The strategy provides an efficient access of psammaplysene analogues that can be explored for potential pharmaceutical or biological activities.
Synthesis of spiro[2.5]octa-4,7-dien-6-one with consecutive quaternary centers via 1,6-conjugate addition induced dearomatization of para-quinone methides
Gai, Kuo,Fang, Xinxin,Li, Xuanyi,Xu, Jinyi,Wu, Xiaoming,Lin, Aijun,Yao, Hequan
supporting information, p. 15831 - 15834 (2015/11/10)
An efficient one-pot approach for the synthesis of spiro[2.5]octa-4,7-dien-6-ones by employing para-quinone methides has been developed. The reaction proceeded smoothly in high yields under mild conditions without the use of metals. Moreover, all products obtained herein contained two or three consecutive quaternary centers.
