33857-20-4Relevant articles and documents
Inhibitors of cholesterol biosynthesis. 2. Hypocholesterolemic and antioxidant activities of benzopyran and tetrahydronaphthalene analogues of the tocotrienols
Pearce,Parker,Deason,Dischino,Gillespie,Qureshi,Volk,Wright
, p. 526 - 541 (2007/10/02)
Tocotrienols exhibit antioxidant and cholesterol-biosynthesis-inhibitory activities and may be of value as antiatherosclerotic agents. The mechanism of their hypolipidemic action involves posttranscriptional suppression of HMG-CoA reductase (HMGR) in a ma