339091-66-6

Basic information

• Product Name: NOREPINEPHRINE L-BITARTRATE HYDRATE, 99%
• Synonyms: α-(aminomethyl)-3,4-dihydroxybenzyl alcohol l-bitartrate
• CAS NO: 339091-66-6
• Molecular Formula: (HO)2C6H3CH(CH2NH2)OHC4H6O6xH2O
• Molecular Weight: 0
• EINECS: 200-095-0
• Mol File: 339091-66-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 781.8°C at 760 mmHg
• Flash Point: 426.6°C
• Appearance: /
• Vapor Pressure: 9.8E-26mmHg at 25°C
• CAS DataBase Reference: NOREPINEPHRINE L-BITARTRATE HYDRATE, 99%(CAS DataBase Reference)
• NIST Chemistry Reference: NOREPINEPHRINE L-BITARTRATE HYDRATE, 99%(339091-66-6)
• EPA Substance Registry System: NOREPINEPHRINE L-BITARTRATE HYDRATE, 99%(339091-66-6)

Safety Data

• Hazard Codes: T+
• Statements: 26/27/28
• Safety Statements: 28-36/37-45
• RIDADR: UN 2811 6.1/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 339091-66-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t;1-,2-;/m.1./s1

Upstream product

• 99-40-1 2-chloro-3',4'-dihydroxyacetophenone 
• 87-69-4 L-Tartaric acid 
• 51-41-2 norepinephrine 

Relevant articles and documents

Method for asymmetrically synthesizing norepinephrine bitartrate

The invention discloses a preparation method for asymmetrically synthesizing norepinephrine bitartrate. The method is characterized by comprising the following steps: by using chloroacetyl catechol asa raw material, asymmetrically reducing carbonyl in the chloroacetyl catechol into hydroxyl, reacting with urotropine, hydrolyzing with hydrochloric acid to obtain R-norepinephrine, salifying rnorepinephrine and Ltartaric acid are salified to obtain norepinephrine bitartrate, wherein the total yield is larger than or equal to 86%, the ee value is larger than or equal to 95%, and the purity is larger than or equal to 99.6%. The method overcomes the defects in the prior art, and has the advantages that asymmetric reduction is adopted, so that the yield of norepinephrine bitartrate is increased,three wastes and the cost are reduced, and the method is suitable for industrial production.