339333-00-5

Basic information

• Product Name: 4-Piperidinepropanoic acid, 1-(phenylmethyl)-
• Synonyms: 3-(1-benzyl-4-piperidyl)propanoic acid;3-(1-Benzyl-piperidin-4-yl)-propionic acid;3-(1-benzylpiperidin-4-yl)propionic acid
• CAS NO: 339333-00-5
• Molecular Formula: C15H21NO2
• Molecular Weight: 247.337
• Mol File: 339333-00-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 78 °C (ethanol)
• CAS DataBase Reference: 4-Piperidinepropanoic acid, 1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinepropanoic acid, 1-(phenylmethyl)-(339333-00-5)
• EPA Substance Registry System: 4-Piperidinepropanoic acid, 1-(phenylmethyl)-(339333-00-5)

Safety Data

• Hazardous Substances Data: 339333-00-5(Hazardous Substances Data)

Upstream product

• 40110-55-2 ethyl 2-(1-benzylpiperidine-4-ylidene)acetate 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 100-39-0 benzyl bromide 
• 71879-55-5 ethyl 3-(piperid-4-yl)propionate 
• 330173-08-5 N-benzyl-2-(4-methylphenylsulfonyl)acetamide 
• 100-46-9 benzylamine 
• 133407-67-7 ethyl (E)-6-(benzyloxy)hex-2-enoate 
• 2564-06-9 N-benzyl-2-chloroacetamide 
• 124438-29-5 3-(1-Benzyl-piperidin-4-yl)-propan-1-ol 
• 124438-69-3 3-(1-Benzyl-piperidin-4-yl)-propionic acid,ethyl ester 

Downstream Products

• 124438-69-3 3-(1-Benzyl-piperidin-4-yl)-propionic acid,ethyl ester 
• 1454273-52-9 ethyl 5-(1-benzylpiperidin-4-yl)-2-diazo-3-oxopentanoate 
• 1454273-53-0 ethyl 8-benzyl-2-oxo-8-azaspiro[4.5]decane-1-carboxylate 
• 1454273-54-1 ethyl 8-benzyl-2-ureido-8-azaspiro[4.5]dec-1-ene-1-carboxylate 
• 1454273-55-2 1'-benzyl-6,7-dihydrospiro[cyclopenta[d]pyrimidine-5.4'-piperidine]-2,4-(1H,3H)-dione 
• 1454273-51-8 ethyl 5-(1-benzylpiperidin-4-yl)-3-oxopentanoate 
• 364385-41-1 methyl (E)-3-{2-[(1-benzyl-4-piperidinyl)ethyl]oxazolo[4,5-b]pyridin-6-yl}-2-propenoate 
• 364385-42-2 methyl 3-{2-[2-(4-piperidinyl)ethyl]oxazolo[4,5-b]pyridin-6-yl}-2-propenoate 
• 364385-39-7 2-[(1-benzyl-4-piperidinyl)ethyl]-6-bromooxazolo[4,5-b]pyridine 

Relevant articles and documents

GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

Disclosed are a gonadotropin releasing hormone receptor antagonist and a pharmaceutical composition including the same, which can be useful in preventing or treating a sex hormone-related disease such as endometriosis, amenorrhea, irregular menstruation, uterine myoma, uterine fibroids, polycystic ovarian disease, lupus erythematous, hypertrichosis, precocious puberty, short stature, acne, alopecia, gonadal steroid-dependent neoplasms, gonadotropin-producing pituitary adenoma, sleep apnea, irritable bowel syndrome, premenstrual syndrome, benign prostatic hyperplasia, contraception, and infertility, as well as Alzheimer disease.

Synthetic study of 4-substituted piperidine ring in elarofiban, RWJ-50042, tirofiban and paroxetine

A new strategy for synthesizing a 4-substituted piperidine ring uses the formal [3+3] cycloaddition reaction as the key protocol. This method provides a convenient formal synthesis of elarofiban, RWJ-50042, tirofiban and paroxetine.