33956-18-2

Basic information

• Product Name: 6-Benzyloxycarbonylamino-2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-hexanoic acid methyl ester
• CAS NO: 33956-18-2
• Molecular Weight: 493.601
• Mol File: 33956-18-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-Benzyloxycarbonylamino-2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-hexanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Benzyloxycarbonylamino-2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-hexanoic acid methyl ester(33956-18-2)
• EPA Substance Registry System: 6-Benzyloxycarbonylamino-2-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-hexanoic acid methyl ester(33956-18-2)

Safety Data

• Hazardous Substances Data: 33956-18-2(Hazardous Substances Data)

Upstream product

• 13850-91-4 Boc-(D,L)-N(Me)-Val-OH 
• 55355-50-5 N^ω-benzyloxycarbonyl-(RS)-lysine methyl ester hydrochloride 
• 13734-41-3 t-Boc-L-valine 
• 27894-50-4 methyl (2S)-2-amino-6-{[(benzyloxy)carbonyl]amino}hexanoate hydrochloride 
• 3392-12-9 Boc-Val-ONSu 
• 24498-31-5 (S)-methyl 2-amino-6-(benzyloxycarbonylamino)hexanoate 

Downstream Products

• 98748-38-0 Z(OMe)-Gly-Val-Val-Lys(Z)-NH-NH₂ 
• 103607-30-3 Z(OMe)-Gly-Val-Val-Lys(Z)-OMe 
• 103607-28-9 Z(OMe)-Val-Val-Lys(Z)-OMe 
• 103607-29-0 H-Val-Val-Lys(Z)-OMe 

Relevant articles and documents

MIXED ANHYDRIDES IN PEPTIDE SYNTHESIS. A STUDY URETHANE FORMATION WITH A CONTRIBUTION ON MINIMIZATION OF RACEMIZATION

A study of the factors contributing to urethane formation during the coupling of N-alkoxycarbonylamino acids with an amino acid ester by the mixed carboxylic-carbonic acid anhydride method has been carried out, using nuclear magnetic resonance spectroscop

Mixed Anhydrides in Peptide Synthesis. Reduction of Urethane Formation and Racemization Using N-Methylpiperidine as the Tertiary Amine Base

The side reactions of urethane formation and racemization accompanying couplings by the mixed anhydride method are reduced when N-methylpiperidine is used as base, the best results being achieved in dichloromethane.