33977-47-8

Basic information

• Product Name: Ba 37768
• CAS NO: 33977-47-8
• Molecular Weight: 211.307
• Mol File: 33977-47-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Ba 37768(CAS DataBase Reference)
• NIST Chemistry Reference: Ba 37768(33977-47-8)
• EPA Substance Registry System: Ba 37768(33977-47-8)

Safety Data

• Hazardous Substances Data: 33977-47-8(Hazardous Substances Data)

Upstream product

• 2876-13-3 N-benzylpyridinium chloride 
• 87372-76-7 β,β-dimethyl-α-phenyl-3-pyridineethanol 
• 87372-77-8 3-(2-chloro-1,1-dimethyl-2-phenylethyl)pyridine 
• 134126-14-0 1-benzyl-4-isopropylidene-1,4-dihydropyridine 

Relevant articles and documents

Mechanism of the Grignard Addition Reaction. XV. The Reaction of Grignard Reagents with Benzylpyridinium Chloride

The reaction of Grignard reagents with benzylpyridinium chloride produces 2-alkyl-N-benzyl-1,2- and 4-alkyl-N-benzyl-1,4-dihydropyridines.The mechanism seems to be polar, concerted except for the t-butylmagnesium reagent.The adducts may reduce the starting material to the unreported, non-alkylated N-benzyl-1,4-dihydropyridine.If the Grignard-alkyl is secondary, crystalline 4-alkylidene-1,4-dihydropyridines may be produced.Thermal rearrangements of N-benzyl-1,4-dihydropyridines lead to migration of the benzyl group.