3400-41-7 Usage
Description
Cyclopentanecarboxamide, N-phenyl-, also known as CyclopentanecarboxaMide, N-phenyl-, is a chemical compound with the molecular formula C12H15NO. It is an amide derivative featuring a cyclopentane ring and a phenyl group attached to the nitrogen atom. CyclopentanecarboxaMide, N-phenylpossesses potential pharmacological properties and is utilized in medicinal chemistry research for the development of new drugs. Additionally, it serves as an intermediate in the synthesis of other organic compounds. Due to its potential hazardous effects on human health and the environment, careful handling is advised.
Uses
Used in Medicinal Chemistry Research:
CyclopentanecarboxaMide, N-phenylis employed as a research compound in medicinal chemistry, where it aids in the development of new drugs. Its unique structure and properties make it a valuable component in the creation of pharmaceuticals with novel therapeutic effects.
Used as an Intermediate in Organic Synthesis:
In the field of organic chemistry, CyclopentanecarboxaMide, N-phenylis used as an intermediate in the synthesis of other organic compounds. Its cyclopentane ring and phenyl group provide a foundation for the construction of more complex molecules with various applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 3400-41-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,0 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3400-41:
(6*3)+(5*4)+(4*0)+(3*0)+(2*4)+(1*1)=47
47 % 10 = 7
So 3400-41-7 is a valid CAS Registry Number.
3400-41-7Relevant articles and documents
Beckmann rearrangement of ketoxime catalyzed by N-methyl-imidazolium hydrosulfate
Hu, Hongyu,Cai, Xuting,Xu, Zhuying,Yan, Xiaoyang,Zhao, Shengxian
, (2018/08/21)
Beckmann rearrangement of ketoxime catalyzed by acidic ionic liquid-N-methyl-imidazolium hydrosulfate was studied. Rearrangement of benzophenone oxime gave the desirable product with 45% yield at 90 ?C. When co-catalyst P2O5 was added, the yield could be improved to 91%. The catalyst could be reused three cycles with the same efficiency. Finally, reactions of other ketoximes were also investigated.
OH-catalyzed amidation of azides and aldehydes: An efficient route to amides
Gu, Lijun,Wang, Wei,Liu, Jiyan,Li, Ganpeng,Yuan, Minglong
supporting information, p. 2604 - 2608 (2016/05/24)
A [bmIm]OH-catalyzed amidation of azides and aldehydes is reported. This reaction is easily handled and proceeds under mild conditions. The overall transformation involves azide-enolate cycloaddition, which subsequently undergoes rearrangement to give amides. Importantly, the employment of ionic liquid makes this transformation green and practical.
Mild and Efficient Cobalt-Catalyzed Cross-Coupling of Aliphatic Amides and Aryl Iodides in Water
Tan, Bryan Yong-Hao,Teo, Yong-Chua
supporting information, p. 1697 - 1701 (2015/07/20)
A convenient protocol for the C-N cross-coupling of aliphatic amides and iodobenzene is demonstrated using a simple and inexpensive Co(C2O4)·2H2O/N,N′-dimethylethylenediamine (DMEDA) catalytic system in water. Good yields of N-arylated products were isolated (up to 85%) and the protocol has been successfully applied to the synthesis of the anticancer drug, flutamide.
