340129-94-4 Usage
Description
(R)-tert-butyl 2-vinylpyrrolidine-1-carboxylate is a chemical compound with the molecular formula C13H23NO2. It is a derivative of pyrrolidine, a five-membered heterocyclic ring compound that contains a nitrogen atom. The tert-butyl group is a bulky substituent attached to the nitrogen atom, while the vinyl group is a two-carbon chain with a double bond. (R)-tert-butyl 2-vinylpyrrolidine-1-carboxylate is commonly used in organic synthesis and pharmaceutical research, as the pyrrolidine moiety is found in many natural products and biologically active molecules. (R)-tert-butyl 2-vinylpyrrolidine-1-carboxylate has potential applications in the development of new drugs and materials due to its unique structural features and reactivity.
Uses
Used in Organic Synthesis:
(R)-tert-butyl 2-vinylpyrrolidine-1-carboxylate is used as a building block for the synthesis of various organic compounds. Its unique structural features and reactivity make it a valuable intermediate in the creation of complex molecules.
Used in Pharmaceutical Research:
(R)-tert-butyl 2-vinylpyrrolidine-1-carboxylate is used as a key component in the development of new drugs. The pyrrolidine moiety, which is present in many biologically active molecules, allows for the design and synthesis of novel pharmaceuticals with potential therapeutic applications.
Used in the Development of New Materials:
(R)-tert-butyl 2-vinylpyrrolidine-1-carboxylate is used as a starting material for the creation of new materials with unique properties. Its structural features and reactivity enable the development of innovative materials for various applications, including but not limited to, the medical, chemical, and materials science industries.
Check Digit Verification of cas no
The CAS Registry Mumber 340129-94-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,0,1,2 and 9 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 340129-94:
(8*3)+(7*4)+(6*0)+(5*1)+(4*2)+(3*9)+(2*9)+(1*4)=114
114 % 10 = 4
So 340129-94-4 is a valid CAS Registry Number.
340129-94-4Relevant articles and documents
Enantioselective Aza-Heck Cyclizations of N-(Tosyloxy)carbamates: Synthesis of Pyrrolidines and Piperidines
Ma, Xiaofeng,Hazelden, Ian R.,Langer, Thomas,Munday, Rachel H.,Bower, John F.
, p. 3356 - 3360 (2019/03/07)
Pd(0)-systems modified with SPINOL-derived phosphoramidate ligands promote highly enantioselective aza-Heck cyclizations of alkenyl N-(tosyloxy)carbamates. The method provides versatile access to challenging N-heterocycles and represents the broadest scope enantioselective aza-Heck protocol developed to date.
Copper mediated scalemic organolithium reagents in alkaloid syntheses
Dieter, R. Karl,Chen, Ningyi,Watson, Rhett T.
, p. 3221 - 3230 (2007/10/03)
Scalemic 2-pyrrolidinylcuprates generated via asymmetric deprotonation of N-Boc-pyrrolidine followed by treatment with THF soluble CuCN·2LiCl react with ω-functionalized vinyl halides to afford 2-alkenyl-N-Boc- pyrrolidines. N-Boc deprotection and cyclization via intramolecular N-alkylation generates the pyrrolizidine or indolizidine skeletons. Subsequent functional group manipulation affords enantioenriched (+)-heliotridane, (+)-isoretronecanol, a formal synthesis of (+)-laburnine, (+)-(R)-2,3,5,7a- tetrahydro-1H-pyrrolizine, (R)-1,2,3,5,6,8a-hexahydroindolizine, (+)-ent-δ-coniceine, (+)-tashiromine and (+)-5-epitashiromine.
