34036-34-5

Basic information

• Product Name: bis(morpholino)(4-methylphenyl)methane
• Synonyms: bis(morpholino)(4-methylphenyl)methane
• CAS NO: 34036-34-5
• Molecular Weight: 276.379
• Mol File: 34036-34-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: bis(morpholino)(4-methylphenyl)methane(CAS DataBase Reference)
• NIST Chemistry Reference: bis(morpholino)(4-methylphenyl)methane(34036-34-5)
• EPA Substance Registry System: bis(morpholino)(4-methylphenyl)methane(34036-34-5)

Safety Data

• Hazardous Substances Data: 34036-34-5(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 113700-15-5 1-(Bromo-p-tolyl-methyl)-pyridinium; bromide 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 1257405-12-1 C₁₉H₂₁ClN₂O₂ 
• 1257405-14-3 C₂₀H₂₄N₂O₂ 
• 1257405-11-0 C₁₉H₂₁N₃O₄ 
• 1257405-15-4 C₂₀H₂₄N₂O₂ 
• 57387-53-8 N-(4-methyl-benzylidene)-2',6'-dimethyl-aniline 
• 641-58-7 4,4'-[(4-methylphenyl)methylene]bis(N,N-dimethylaniline) 
• 104-87-0 4-methyl-benzaldehyde 
• 23837-43-6 4-(p-tolyl-o-tolylsulfanyl-methyl)-morpholine 
• 23837-42-5 4-(phenylsulfanyl-p-tolyl-methyl)-morpholine 
• 40891-10-9 N,N′?(4?methylbenzylidene)bisbenzamide 
• 31814-58-1 N-[(acetylamino)(4-methylphenyl)methyl]acetamide 

Relevant articles and documents

Rediscovering aminal chemistry: Copper(ii) catalysed formation under mild conditions

Aminals, the N,N analogues of acetals, have been thoroughly explored in organic chemistry, with a particular focus on heteroaromatic aldehyde lithiation. Nevertheless, the existing methodologies for their formation typically employ harsh conditions limiting their usefulness. In this work, we present an efficient and mild methodology for the preparation of aminals from aromatic aldehydes, including furanic platforms. These mild conditions allowed ease of access to a plethora of aminals and as such we set out to explore previously unaccessible potential applications. By studying the stability of various aminals, we were able to develop a simple aldehyde protecting group based on a commercial diamine which is deprotected under mind conditions. We developed a protocol for the scavenging of genotoxic aldehydes by taking advantage of our methodology and a diamine resin, as well as early studies on the development of a stimuli-responsive release system using a salycil aldehyde derived aminal. This journal is

Novel synthesis of α-acetylstyrylphosphonates

α-Acetylstyrylphosphonates were conveniently synthesized from 2-oxopropylphosphonates and substituted (dimorpholinomethyl)-benzenes (animals). 4-Benzylidenemorpholinium carboxylates, generated from animals by the action of α-halo acids, reacted with the phosphonates to give the products by elimination of the amine. The yields were influenced by the nature of substituents and their position in the phenyl ring and could be improved by adjustment of the acidities of the reacted acids. α-Acetylstyrylphosphonates containing various substituents on every position (at the 2-, 3-, or 4-position) in the phenyl ring were obtained generally in excellent yields using monochloroacetic acid.