3404-72-6Relevant articles and documents
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Takegami et al.
, p. 1478 (1970)
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Dichloropalladium(II): An Effective Catalyst for Cross-Coupling of secondary and Primary Alkyl Grignard and Alkylzinc Reagents with Organic Halides
Hayashi, Tamio,Konishi, Mitsuo,Kobori, Yuji,Kumada, Makoto,Higuchi, Taiichi,Hirotsu, Ken
, p. 158 - 163 (2007/10/02)
Several phosphine-palladium and -nickel complexes were examined for their catalytic activity in the reaction of sec-butylmagnesium chloride with bromobenzene, (E)-β-bromostyrene, 4-bromoanisole, and 2-bromotoluene.Dichloropalladium(II) was found to be by far the most active and selective catalyst to give the corresponding sec-butyl derivatives in high yields with no byproducts.The palladium-dppf complex was also found highly effective in catalyzing the reaction of n-butylmagnesium chloride and sec- and n- butylzinc chloride with organic bromides to give the corresponding cross-coupling products in high yields.The structure of PdCl2(dppf) has been determined by an X-ray diffraction study.It is proposed that the high efficiency of PdCl2(dppf) catalyst can be ascribed to its large P-Pd-P angle and small Cl-Pd-Cl angle.
