34084-81-6

Basic information

• Product Name: 1,3-Cyclohexanedione, 2-(3-oxobutyl)-
• Synonyms: 6-Hydroxy-3-oxo-2-<3-oxo-butyl>-2,3-dihydro-pyridazin;2-<2-Acetyl-aethyl>-cyclohexan-1.3-dion;2-<3-Oxo-butyl>-dihydroresorcin
• CAS NO: 34084-81-6
• Molecular Formula: C10H14O3
• Molecular Weight: 182.219
• Mol File: 34084-81-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1,3-Cyclohexanedione, 2-(3-oxobutyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Cyclohexanedione, 2-(3-oxobutyl)-(34084-81-6)
• EPA Substance Registry System: 1,3-Cyclohexanedione, 2-(3-oxobutyl)-(34084-81-6)

Safety Data

• Hazardous Substances Data: 34084-81-6(Hazardous Substances Data)

Usage

Physical state

Yellow to green crystalline solid

Usage

Reagent in organic synthesis

Applications

a. Acetylating agent in the preparation of heterocyclic compounds
b. Reactant in the synthesis of pharmaceuticals and natural products
c. Flavoring agent in the food industry

Hazardous nature

Potentially hazardous chemical

Safety measures

Proper safety measures should be taken when handling

Upstream product

• 504-02-9 1,3-cylohexanedione 
• 78-94-4 methyl vinyl ketone 

Downstream Products

• 31526-72-4 3-methoxy-2-(3-oxo-butyl)-cyclohex-2-enone 
• 1108206-36-5 2-allyl-2-(3-oxobutyl)-1,3-cyclohexanedione 
• 7195-71-3 3-(2-methyl-6-oxo-cyclohex-1-enyl)-propionic acid 

Relevant articles and documents

Structural diversity and similar bioactivity in synthetic bicyclononanes

Simple syntheses of diverse bicyclo[3.3.1]nonanes and related compounds as the minimal substructure of bioactive natural products via Michael, aldol, and alkylation reactions from diketones are described herein. The structures of the synthesized compounds

ZrCl4-catalyzed Michael reaction of 1,3-dicarbonyls and enones under solvent-free conditions

ZrCl4 has been found to catalyze the conjugate addition of 1,3-dicarbonyl compounds with enones. The reaction does not require any solvent and proceeds smoothly at room temperature leading to the corresponding adduct in good yields.

Indium(III) chloride catalyzed conjugate addition of 1,3-dicarbonyl compounds to α,β-unsaturated ketones

Indium trichloride catalyzes efficiently the Michael reactions of 1,3-dicarbonyl compounds with α,β-unsaturated ketones to afford the corresponding Michael adducts in high yields with high selectivity.