34218-86-5 Usage
Description
O2',3'-dimethyl-cytidine is a chemical compound derived from cytidine nucleoside, featuring two methyl groups attached to the oxygen atoms at the 2' and 3' positions on the ribose sugar. This modification can influence the stability, structure, and function of the cytidine nucleoside. It is present in various biological molecules, including RNA, where it contributes to the regulation of gene expression and protein synthesis. While its specific role and biological significance are under investigation, it is thought to impact the overall activity of RNA molecules and their capacity to manage cellular processes. O2',O3'-dimethyl-cytidine may also hold potential in the development of therapeutic strategies for RNA-based diseases.
Uses
Used in Pharmaceutical Applications:
O2',3'-dimethyl-cytidine is utilized as a key component in the development of novel therapeutic strategies targeting RNA-based diseases. Its unique structure and function within RNA molecules make it a promising candidate for the creation of new drugs that can modulate gene expression and protein synthesis, potentially leading to treatments for a variety of conditions.
Used in Research and Development:
In the field of molecular biology and genetics, O2',3'-dimethyl-cytidine is employed as a valuable tool for studying the role of chemical modifications in RNA function. Its presence in RNA molecules allows researchers to investigate the mechanisms behind gene regulation and protein synthesis, furthering our understanding of cellular processes and the potential for targeted therapeutic interventions.
Used in Diagnostic Applications:
O2',3'-dimethyl-cytidine may also find use in the development of diagnostic tools and tests, particularly for conditions related to RNA function and gene expression. By detecting the presence or levels of this modified nucleoside in biological samples, it could be possible to identify specific disease markers or monitor the effectiveness of RNA-targeted therapies.
Used in Biochemical and Molecular Biology Education:
As a unique and important chemical compound, O2',3'-dimethyl-cytidine can be incorporated into educational materials and curricula related to biochemistry, molecular biology, and genetics. It can serve as a practical example for teaching students about the role of chemical modifications in RNA function and the potential for developing new therapeutic strategies based on these modifications.
Check Digit Verification of cas no
The CAS Registry Mumber 34218-86-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,2,1 and 8 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 34218-86:
(7*3)+(6*4)+(5*2)+(4*1)+(3*8)+(2*8)+(1*6)=105
105 % 10 = 5
So 34218-86-5 is a valid CAS Registry Number.
34218-86-5Relevant articles and documents
Methylation study of ribonucleosides, deoxyribonucleosides, and 2′-O-methylribonucleosides with trimethylsulphonium hydroxide and trimethylsulphonium iodide. Influence of the 2′-hydroxy-groups on the reactivity of the base moieties of ribonucleosides
Yamauchi, Kiyoshi,Nakagima, Toru,Kinoshita, Masayoshi
, p. 2787 - 2792 (2007/10/02)
Methylations of the naturally occuring ribonucleoside (1), deoxyribonucleoside (2), and 2′-O-methylribonucleoside (3) were carried out using trimethylsulphonium hydroxide (Me3SOH) and trimethylsulphonium iodide (Me3Sl). The base moiety of (2) and (3) are more reactive than the corresponding base moiety of (1). The sites and extent of methylation of (2) are considerably different from those of (1), but are almost identical with those of (3). The reactivities of (1)-(3) are discussed in connection to an intramolecular interaction of the 2′-OH groups with the base moiety of (1). The methylating characteristics of Me 3SOH and Me3Sl are also described. The kinetics indicate an SN2 mechanism for methylation of nucleosides by Me 3S+ ions.
