34235-82-0

Basic information

• Product Name: NEPSILON-CARBOBENZOXY-NALPHA-TOSYL-L-LYSINE
• Synonyms: (2S)-6-{[(benzyloxy)carbonyl]amino}-2-{[(4-methylphenyl)sulfonyl]amino}hexanoic acid;Nalpha-Tosyl-Nepsilon-Z-L-lysine;-Carbobenzoxy-Nα-tosyl-L-lysine;-2-(4-methylphenylsulfonamido);EPSILON-CBZ-ALPHA-TOSYL-L-LYS;NEPSILON-CARBOBENZOXY-NALPHA-TOSYL-L-LYSINE;NEPSILON-CBZ-NALPHA-TOSYL-L-LYSINE
• CAS NO: 34235-82-0
• Molecular Formula: C₂₁H₂₆N₂O₆S
• Molecular Weight: 434.51
• Product Categories: Amino Acids;Amino Acids (N-Protected);Biochemistry;Cbz-Amino Acids
• Mol File: 34235-82-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 123 °C
• Appearance: /
• Refractive Index: 14.5 ° (C=1, EtOH)
• Storage Temp.: 2-8°C
• Solubility: almost transparency in hot Toluene
• CAS DataBase Reference: NEPSILON-CARBOBENZOXY-NALPHA-TOSYL-L-LYSINE(CAS DataBase Reference)
• NIST Chemistry Reference: NEPSILON-CARBOBENZOXY-NALPHA-TOSYL-L-LYSINE(34235-82-0)
• EPA Substance Registry System: NEPSILON-CARBOBENZOXY-NALPHA-TOSYL-L-LYSINE(34235-82-0)

Safety Data

• Hazardous Substances Data: 34235-82-0(Hazardous Substances Data)

Usage

General Description

NEPSILON-CARBOBENZOXY-NALPHA-TOSYL-L-LYSINE is a chemical compound commonly used in the field of biochemistry and molecular biology. It is a derivative of the amino acid lysine, commonly known as a protease inhibitor. NEPSILON-CARBOBENZOXY-NALPHA-TOSYL-L-LYSINE is often used in research to study cellular processes and enzyme activity. It is also used in the purification and isolation of enzymes, and in the development of pharmaceuticals. Additionally, NEPSILON-CARBOBENZOXY-NALPHA-TOSYL-L-LYSINE has been studied for its potential in cancer treatment and as a potential therapy for certain inflammatory diseases. Overall, this compound plays a significant role in various biochemical and pharmacological studies and has the potential for further medical applications.

InChI:InChI=1/C21H26N2O6S/c1-16-10-12-18(13-11-16)30(27,28)23-19(20(24)25)9-5-6-14-22-21(26)29-15-17-7-3-2-4-8-17/h2-4,7-8,10-13,19,23H,5-6,9,14-15H2,1H3,(H,22,26)(H,24,25)/t19-/m0/s1

Upstream product

• 657-27-2 L-Lysine hydrochloride 
• 501-53-1 benzyl chloroformate 
• 300594-05-2 4-[2-Oxo-3-(toluene-4-sulfonyl)-oxazolidin-(4E)-ylidene]-butyraldehyde 
• 912806-83-8 (S)-N-tosyl-4-((4'-dibenzylamino)butyl)-1,3-oxazolidin-2-one 
• 912806-84-9 (2S)-6-dibenzylamino-2-tosylaminohexanol 
• 912806-74-7 (S)-(+)-N-tosyl-4-(4',4'-diethoxybutyl)-1,3-oxazolidin-2-one 
• 912806-73-6 (E)-N-tosyl-4-(4',4'-diethoxybutylidene)-1,3-oxazolidin-2-one 
• 912806-85-0 (2S)-2-tosylamino-6-benzyloxycarbonylaminohexanol 
• 1155-64-2 N₆-[(benzyloxy)carbonyl]-L-lysine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 121255-30-9 4-{[N⁶-benzyloxycarbonyl-N²-(toluene-4-sulfonyl)-L-lysyl]-amino}-benzoic acid benzyl ester 
• 997-68-2 D-Allosaccharopin 
• 997-68-2 L-Saccharopine 
• 10317-88-1 N_α-tosyl-L-lysine-ethylester 
• 5853-83-8 N⁶-L-β-aspartyl-L-lysine 
• 6366-86-5 α-L-Asp-ε-L-Lys 
• 132130-13-3 N-((S)-2-oxo-hexahydro-azepin-3-yl)-toluene-4-sulfonamide 
• 118982-49-3 N-[N⁶-benzyloxycarbonyl-N²-(toluene-4-sulfonyl)-L-lysyl]-glycine 
• 103644-54-8 N-[N⁶-benzyloxycarbonyl-N²-(toluene-4-sulfonyl)-L-lysyl]-glycine amide 
• 110663-53-1 N-[N⁶-carbamimidoyl-N²-(toluene-4-sulfonyl)-L-lysyl]-glycine 
• 102373-49-9 N⁶-benzyloxycarbonyl-N²-(toluene-4-sulfonyl)-L-lysine amide 
• 853-17-8 N-[N²-(toluene-4-sulfonyl)-L-lysyl]-glycine 
• 95618-72-7 N²-(toluene-4-sulfonyl)-L-lysine benzyl ester 
• 6072-04-4 (S)-methyl 6-amino-2-(4-methylphenylsulfonamido)hexanoate 

Relevant articles and documents

Nitrile Synthesis by Aerobic Oxidation of Primary Amines and in situ Generated Imines from Aldehydes and Ammonium Salt with Grubbs Catalyst

Herein, a Grubbs-catalyzed route for the synthesis of nitriles via the aerobic oxidation of primary amines is reported. This reaction accommodates a variety of substrates, including simple primary amines, sterically hindered β,β-disubstituted amines, allylamine, benzylamines, and α-amino esters. Reaction compatibility with various functionalities is also noted, particularly with alkenes, alkynes, halogens, esters, silyl ethers, and free hydroxyl groups. The nitriles were also synthesized via the oxidation of imines generated from aldehydes and NH4OAc in situ. (Figure presented.).