34284-44-1

Basic information

• Product Name: Cyclohexane, 1-methoxy-1-methyl-
• Synonyms: 1-Methyl-1-methoxy-cyclohexan;1-Methyl-1-methoxycyclohexane;Cyclohexane,1-methoxy-1-methyl;1-Methoxy-1-methyl-cyclohexan;1-Methoxy-methyl-cyclohexan
• CAS NO: 34284-44-1
• Molecular Formula: C8H16O
• Molecular Weight: 128.214
• Mol File: 34284-44-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Cyclohexane, 1-methoxy-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexane, 1-methoxy-1-methyl-(34284-44-1)
• EPA Substance Registry System: Cyclohexane, 1-methoxy-1-methyl-(34284-44-1)

Safety Data

• Hazardous Substances Data: 34284-44-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 591-49-1 1-methylcyclohex-1-ene 
• 38772-60-0 2-Bromo-1-methoxy-1-methyl-cyclohexane 
• 623-26-7 terephthalonitrile 
• 4313-57-9 2,5-dihydrotoluene 
• 590-67-0 1-Methylcyclohexanol 
• 74-88-4 methyl iodide 
• 1638-26-2 1,1-Dimethylcyclopentane 
• 7664-93-9 sulfuric acid 
• 108-94-1 cyclohexanone 
• 1129-35-7 4-cyanobenzoic acid methyl ester 
• 1192-37-6 methylenecyclohexane 
• 186581-53-3 diazomethane 

Downstream Products

• 931-77-1 1-bromo-1-methylcyclohexane 

Relevant articles and documents

Hydride-Transfer Reactions in the Gas Phase. 2. Anchimeric Assistance in the H(-) Transfer from 1,1-Dimethylcyclopentane to Alkyl Cations

The gas-phase hydride transfer from the title compound to several ionic acceptors GA(+) = CH5(+), C2H5(+), s-C3H7(+), and t-C4H9(+) was studied by mass spectrometric and radiolytic methods in the pressure range 1.1E-8 - 700 Torr.Analysis of the irradiated mixtures points to the exclusive formation of rearranged products, with those with methyl migration prevailing over those with ring expansion.Thermochemical considerations, isotope labeling experiments, and deuterium isotope effect measurements concur in defining the detailed mechanism of the gas-phase hydride transfer, which involves significant anchimeric assistance of the methyl and methylene groups adjacent to the reaction center.The primary and the secondary α-D kinetic isotope effects, measured in the hydride transfer from the methylene moieties adjacent to the quaternary carbon of tthe title compound to either s-C3H7(+) or t-C4H9(+), amount to 2.70 (s-C3H7(+)) and 1.89 (t-C4H9(+)) and to 1.77 (s-C3H7(+)) and 1.15 (t-C4H9(+)), respectively.These values are interpreted in terms of a transition state, which is placed rather late along the reaction coordinate, and wherein the assistance of the neighboring (methyl or methylene) group to the departing hydride increases by decreasing the strength of the GA(+) acceptor.The results obtained from the present gas-phase investigation are discussed and compared with those of related gas-phase and solution data.

Microwave mediated protection of hindered phenols and alcohols

Hindered phenols and alcohols were protected as their corresponding ethers using different alkylating agents in presence of KOH/DMSO under microwave irradiation.

Effective Au(III)-CuCl2-catalyzed addition of alcohols to alkenes

Alkenes can be activated by Au(III) catalysts, and the effective addition of alcohols to alkenes can be carried out under mild conditions with Au(III), provided that catalytic amounts of CuCl2 are added, which significantly stabilize the cationic Au(III). The Royal Society of Chemistry.