342884-62-2 Usage
Biological Activity
Potent and highly selective non-peptide δ receptor antagonist (K i values are 4.7, 3800 and 7900 nM for δ , κ and μ receptors respectively). More selective than naltrindole (17-(Cyclopropylmethyl)-6,7-dehydro-4,5a-epoxy-3,14-dihydroxy-6,7-2',3'-indolomorphinan hydrochloride ).
Check Digit Verification of cas no
The CAS Registry Mumber 342884-62-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,2,8,8 and 4 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 342884-62:
(8*3)+(7*4)+(6*2)+(5*8)+(4*8)+(3*4)+(2*6)+(1*2)=162
162 % 10 = 2
So 342884-62-2 is a valid CAS Registry Number.
342884-62-2Relevant articles and documents
Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5α-epoxy-3,14-dihydroxy-6,7:2′, 3′-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy
McLamore,Ullrich,Rothman,Xu,Dersch,Coop,Davis,Porreca,Jacobson,Rice
, p. 1471 - 1474 (2001)
The N-alkyl analogues (N-ethyl through N-heptyl), branched N-alkyl chain analogues (N-isopropyl, N-2-methylpropyl, and N-3-methylbutyl), and N-alkenyl analogues ((E)-N-3-methylallyl (crotyl), N-2-methylallyl, and N-3,3-dimethylallyl) were prepared in the
