34296-51-0

Basic information

• Product Name: 1-PHENYL-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE
• Synonyms: 1-PHENYL-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE;1-Phenyl-1H-1,2,3-trizole-4-carbaldehyde
• CAS NO: 34296-51-0
• Molecular Formula: C₉H₇N₃O
• Molecular Weight: 173.17
• Mol File: 34296-51-0.mol
• Article Data: 44

Chemical Properties

• Melting Point: 99-101°
• Boiling Point: 359.8°C at 760 mmHg
• Flash Point: 171.4°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 2.32E-05mmHg at 25°C
• Refractive Index: 1.642
• CAS DataBase Reference: 1-PHENYL-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-PHENYL-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE(34296-51-0)
• EPA Substance Registry System: 1-PHENYL-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE(34296-51-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 34296-51-0(Hazardous Substances Data)

Usage

General Description

1-PHENYL-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE is an organic compound with the molecular formula C10H8N4O. It is a carbonyl compound that contains a 1,2,3-triazole ring and a phenyl group. This chemical is commonly used in organic synthesis and pharmaceutical research as a building block for the preparation of various pharmacologically active compounds. It can also be utilized as a reagent in the synthesis of heterocyclic compounds and as a fluorescent probe in analytical chemistry. 1-PHENYL-1H-1,2,3-TRIAZOLE-4-CARBALDEHYDE has potential applications in the development of new drugs, agrochemicals, and materials.

InChI:InChI=1/C9H7N3O/c13-7-8-6-12(11-10-8)9-4-2-1-3-5-9/h1-7H

Upstream product

• 624-67-9 Propargylic aldehyde 
• 622-37-7 Phenyl azide 
• 103755-58-4 (1-phenyl-1H-1,2,3-triazole-4-yl)methanol 
• 107-19-7 propargyl alcohol 
• 14925-39-4 2-bromoacrolein 
• 108-86-1 bromobenzene 
• 62-53-3 aniline 
• 113934-26-2 1-(4-nitrophenyl)-1H-1,2,3-triazole-4-carboxaldehyde 
• 10160-87-9 Propiolaldehyde diethyl acetal 
• 2055-52-9 methyl 1-phenyl-1H-1,2,3-triazole-4-carboxylate 
• 50704-41-1 2-diazo-malonaldehyde 
• 1750-36-3 (E)-N-benzylidenebenzenamine 
• 1012081-57-0 C₁₃H₁₇N₃O₂ 
• 90886-87-6 1‐(4‐nitrophenyl)‐1H‐1,2,3‐triazole‐4‐yl‐methanol 

Downstream Products

• 103755-58-4 (1-phenyl-1H-1,2,3-triazole-4-yl)methanol 
• 4600-04-8 1-phenyl-1H-[1,2,3]triazole-4-carboxylic acid 
• 3198-98-9 dimethyl 1-phenyl-1H-pyrazole-3,4-dicarboxylate 
• 915363-17-6 C₂₅H₁₆BrClFN₇ 

Relevant articles and documents

[HDBU][HSO4]-catalyzed facile synthesis of new 1,2,3-triazole-tethered 2,3-dihydroquinazolin-4[1H]-one derivatives and their DPPH radical scavenging activity

A simple and efficient protocol has been developed for the synthesis of new1,2,3-triazole-2,3-dihydroquinazolin-4[1H]-one (DHQ) conjugates(6a?j) via ultrasound-assisted, solvent-free ionic liquid [HDBU][HSO4]-catalyzed reaction in good to excellent yields. This non-conventional, ultrasound-assisted route has taken the reactions over the conventional reflux method to provide good to excellent yields of the corresponding products (6a?j) in a very short time. In addition, mild reaction conditions, tolerance to functionalized substrates, ease of product isolation, prevention of its over oxidation and reusability of catalyst [HDBU][HSO4] are some key striking features of the methodology. The newly synthesized derivatives (6a?j) were screened for antioxidant activity using 1,1-diphenyl-2-picryl hydrazyl (DPPH) assay and are found to be a potent scavenger. The compounds 6b, 6c, 6d, 6e and 6i showed significant antioxidant activity. Molecular docking studies showed significant binding affinity in the active site of myeloperoxidase (MPO) enzyme and hence scavenged by inhibition of MPO. In silico ADMET and pharmacokinetic studies of the conjugates are very promising; a cumulative body of evidence suggests their medicinal value as a potential orally active drug candidate. Graphical abstract: [Figure not available: see fulltext.]

Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles

A series of 6-amidinobenzothiazoles, linked via phenoxymethylene or directly to the 1,2,3-triazole ring with a p-substituted phenyl or benzyl moiety, were synthesised and evaluated in?vitro against four human tumour cell lines and the protozoan parasite T

Synthesis and characterization of 1,2,3-triazole containing Fe(II) sensor

A new bis(1,2,3-triazolyl) imine based probe was designed and synthesized. Chemical structure of the probe was confirmed by IR, 1H and 13C NMR spectroscopy. The probe was investigated for its recognition abilities in aqueous-organic