34308-25-3

Basic information

• Product Name: 1-METHYLADENOSINE HYDROIODIDE
• Synonyms: N1-METHYLADENOSINE HYDROIODIDE;1-METHYLADENOSINE HYDROIODIDE;1-methyladenosine hydriodide
• CAS NO: 34308-25-3
• Molecular Formula: C11H16IN5O4
• Molecular Weight: 409.18
• Mol File: 34308-25-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 655.4 °C at 760 mmHg
• Flash Point: 350.2 °C
• Appearance: /
• Density: 1.88 g/cm³
• Storage Temp.: −20°C
• CAS DataBase Reference: 1-METHYLADENOSINE HYDROIODIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYLADENOSINE HYDROIODIDE(34308-25-3)
• EPA Substance Registry System: 1-METHYLADENOSINE HYDROIODIDE(34308-25-3)

Safety Data

• Hazardous Substances Data: 34308-25-3(Hazardous Substances Data)

Usage

General Description

1-Methyladenosine Hydroiodide is a chemical compound characterized by the integration of a methyl group into an adenosine molecule, while the hydroiodide is typically added for stability purposes or to make the compound soluble in water. Its molecular formula is C11H16IN5O4. It isn't extensively researched or widely used, so there is limited information about its properties, use, or associated hazards. Always consult material safety data sheets and applicable safety protocols when handling this or any chemical substance.

Upstream product

• 58-61-7 adenosine 
• 74-88-4 methyl iodide 

Downstream Products

• 26001-41-2 1-methyl-6-thio-inosine 

Relevant articles and documents

Synthesis of a peptide nucleic acid with a novel 1-methyl-6-mercaptopurine base

(Chemical Equation Presented) A novel peptide nucleic acid (PNA) monomer 16 containing a novel 1-methyl-6-mercaptopurine base was synthesized by coupling the in situ generated acid chloride of (1-methyl-6-mercaptopurin-9-yl)acetic acid (6) into an L-lysine backbone (13) using 10% CCl4 in pyridine and Ph3P. Compound 6 was synthesized from 6-mercapto-1-methylpurine and ethylbromoacetate in the presence of NaH followed by alkaline hydrolysis and subsequent neutralization with a cation exchange resin. The L-lysine backbone (13) was obtained by the reaction of Nε-CBZ-L-lysine allyl ester with Boc-aminoactaldehyde in the presence of NaBH3CN under reductive amination conditions. Oligomerization of the monomer 16 to PNA analogues was achieved using BOC-BHA-PEG-PS resin as a solid support and the in situ generated acid chloride of 16 by 10% CCl4 in DCM in the presence of Ph 3P.