343221-63-6

Basic information

• Product Name: 2-[(2,4-dichlorophenyl)amino]pyridine-3-carboxylic acid
• Synonyms: 2-[(2,4-dichlorophenyl)amino]pyridine-3-carboxylic acid
• CAS NO: 343221-63-6
• Molecular Weight: 283.114
• Mol File: 343221-63-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-[(2,4-dichlorophenyl)amino]pyridine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2,4-dichlorophenyl)amino]pyridine-3-carboxylic acid(343221-63-6)
• EPA Substance Registry System: 2-[(2,4-dichlorophenyl)amino]pyridine-3-carboxylic acid(343221-63-6)

Safety Data

• Hazardous Substances Data: 343221-63-6(Hazardous Substances Data)

Upstream product

• 2942-59-8 2-chloronicotinic acid 
• 554-00-7 2,4-Dichloroaniline 
• 1452-94-4 ethyl 2-chloronicotinate 
• 115800-79-8 ethyl 2-(2,4-dichloro anilino)nicotinate 

Downstream Products

• 1350515-61-5 N₃-[6-(methyloxy)-1,3-benzothiazol-2-yl]-2-[(2,4-dichlorophenyl)amino]-3-pyridinecarboxamide 
• 1350515-68-2 N-3-[6-(nitro-1,3-benzothiazol-2-yl)]-2-[(2,4-dichlorophenyl)amino]-3-pyridinecarboxamide 
• 1350515-73-9 2-[2-(2,4-dichloroanilino)-3-pyridyl]-10-methyl-5,10-dihydro-5λ6-benzo[e][1,2,4]triazolo[1,5-b][1,2,4]thiadiazine-5,5-dione 
• 1350515-77-3 2-[2-(2,4-dichloroanilino)-3-pyridyl]-10-phenyl-5,10-dihydro-5λ6-benzo[e][1,2,4]triazolo[1,5-b][1,2,4]thiadiazine-5,5-dione 
• 1393658-13-3 N₃-(6-fluoro-1,3-benzothiazol-2-yl)-2-(2,4-dichloroanilino)nicotinamide 
• 136280-60-9 (2,4-Dichloro-phenyl)-(3-phenylsulfanylmethyl-pyridin-2-yl)-amine 
• 127555-33-3 1-(2,4-dichlorophenyl)-1,3-dihydro-3,3-dimethyl-2H-pyrrolo[2,3-b]pyridin-2-one 

Relevant articles and documents

Synthesis and biological evaluation of new heteroaryl carboxylic acid derivatives as anti-inflammatory-analgesic agents

A series of nicotinic acid derivatives structurally related to niflumic acid and certain pyridazine-containing compounds have been synthesized and characterized by analytical and spectral data. All compounds were screened for their potential analgesic and

Synthesis of 2-(arylamino)nicotinic acids in high-temperature water

In hydrothermal reactions at 150-180 °C, 2-(arylamino)nicotinic acids were synthesized by amination of 2-chloronicotinic acid with aromatic amine derivatives, with potassium carbonate as base. The procedure is efficient, environmentally friendly, and practical, with moderate to excellent yields (up to 98%). Springer Science+Business Media B.V. 2012.

Catalyst-free amination of 2-chloronicotinic acid in water under microwave irradiation

A simple, efficient and environmental friendly method for the synthesis of 2-arylaminonicotinic acids derivatives by reacting 2-chloronicotinic acid with anilines with potassium carbonate as the base and water as the media under microwave irradiation is described. The synthesis of 2-arylaminonicotinic acids is important because they are nonsteroidal anti-inflammatory drugs.