34331-40-3Relevant articles and documents
EFFECT OF CRYSTAL PACKING ON THE SOLID-STATE SPECTRAL PROPERTIES OF VICINAL DIKETONES.
Crowley,Balanson,Mayerle
, p. 6416 - 6422 (1983)
X-ray crystal structures are reported for six substituted benzils: 4,4 prime -dimethoxy(1), 4-ethoxy, 4,4 prime -diethoxy(6), and the meso, racemic, and LL chiral, bis-4,4 prime -(2,2 prime -dimethyl-1,3-dioxacyclopentyl-4-methoxy) benzils. The packing mo
Metabolism of 2,3-dihydroxypropane-1-sulfonate by marine bacteria
Celik, Ersin,Maczka, Michael,Bergen, Nils,Brinkhoff, Thorsten,Schulz, Stefan,Dickschat, Jeroen S.
, p. 2919 - 2922 (2017)
Both enantiomers of the sulfoquinovose breakdown product 2,3-dihydroxypropane-1-sulfonate, an important sulfur metabolite produced by marine algae, were synthesised in a 34S-labelled form and used in feeding experiments with marine bacteria. The labelling was efficiently incorporated into the sulfur-containing antibiotic tropodithietic acid and sulfur volatiles by the algal symbiont Phaeobacter inhibens, but not into sulfur volatiles released by marine bacteria associated with crustaceans. The ecological implications and the relevance of these findings for the global sulfur cycle are discussed.
BIHETEROCYCLIC COMPOUND
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Paragraph 1087-1089; 1124-1126, (2019/02/01)
The present invention provides a compound of formula (1) and a pharmaceutical composition comprising the compound useful as a nerve regeneration promoter wherein R1-L- is R1—OC(O)—, or the like, R1 is hydrogen atom, optionally-substituted C1-6 alkyl group, optionally-substituted 3- to 8-membered cycloalkyl group, or the like, R2 is hydrogen atom or the like, Ring A is formula (2) or formula (3) wherein R3 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like, the part of X, Y, and Z is X═Y—Z, X—Y═Z, or X—Y—Z, X is nitrogen atom, NR4 (R4 is hydrogen atom, optionally-substituted C1-6 alkyl group, or the like), or the like, Y is carbon atom or the like, and Z is carbon atom, nitrogen atom or the like.
PYRIDINYL BASED APOPTOSIS SIGNAL-REGULATION KINASE INHIBITORS
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Paragraph 0576, (2018/09/12)
Apoptosis signal-regulating kinase 1 (ASK1) activation and signaling have been reported to play an important role in a broad range of diseases including neurodegenerative, cardiovascular, inflammatory, autoimmunity and metabolic disorders. Disclosed herein is the synthesis of pyridinyl derived therapeutic agents that function as inhibitors of ASK 1 as well as their pharmaceutical compositions and methods of use.