34352-84-6

Basic information

• Product Name: 1,1'-Biphenyl, 4-(1-methylethenyl)-
• CAS NO: 34352-84-6
• Molecular Formula: C15H14
• Molecular Weight: 194.276
• Mol File: 34352-84-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,1'-Biphenyl, 4-(1-methylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-Biphenyl, 4-(1-methylethenyl)-(34352-84-6)
• EPA Substance Registry System: 1,1'-Biphenyl, 4-(1-methylethenyl)-(34352-84-6)

Safety Data

• Hazardous Substances Data: 34352-84-6(Hazardous Substances Data)

Usage

Physical state

Colorless, waxy solid

Solubility

Insoluble in water; soluble in organic solvents

Uses

a. Production of polymer materials
b. Fragrance ingredient in perfumes and cosmetics
c. Manufacture of pharmaceuticals
d. Flavoring agent in food products

Toxicity

Low toxicity

Environmental impact

Low environmental impact

Safety

Handle with care and use in accordance with safety guidelines

Upstream product

• 75-24-1 trimethylaluminum 
• 14002-51-8 4-biphenyl-carboxylic acid chloride 
• 7116-95-2 4-isopropylbiphenyl 
• 67-71-0 dimethylsulfone 
• 3597-91-9 biphenyl-4-yl methanol 
• 34352-74-4 2-biphenyl-4-yl-propan-2-ol 

Downstream Products

• 60106-64-1 β-Methyl<1,1'-biphenyl>-4-propanenitrile 
• 92-91-1 biphenyl-4-acetaldehyde 
• 75-89-8 2,2,2-trifluoroethanol 
• 75-90-1 2,2,2-Trifluoroacetaldehyde 
• 1344026-87-4 4-(1,3,3-trimethyl-6-phenylindan-1-yl)biphenyl 

Relevant articles and documents

Synthesis of 2-Substituted Propenes by Bidentate Phosphine-Assisted Methylenation of Acyl Fluorides and Acyl Chlorides with AlMe3

Bidentate phosphine-assisted methylenation of acyl fluorides and acyl chlorides with substituted with aryl, alkenyl, and alkyl groups trimethylaluminum afforded an array of 2-substituted propene derivatives. The addition of a catalytic amount of DPPM increased an efficiency of the reactions. Trimethylaluminum as the methylenation reagent not only eliminates the presynthesis of methylene transfer reagent, but provides an efficient method for the synthesis of a series of 2-substituted propenes.

The cumene/O2 system: A very simple tool for the radical chain oxidation of some functional groups

Due to the relative stability of the cumyl radical, cumenes and α-methyl-styrenes are ideally structured to directly harvest the oxidizing reactivity of O2 and initiate radical chain reactions in catalyst-free conditions. In the absence of additional substrates, these processes can lead to acetophenones. In the presence of substrates, the cumene oxidation process can be intercepted in various chain reactions, affording very simple protocols for functional group oxidation.

Efficient Synthesis and Resolution of trans-2-(1-Aryl-1-methylethyl)cyclohexanols; Practical Alternatives to 8-Phenylmenthol

A short synthesis and resolution of effective chiral auxiliaries of the 8-arylmenthol-type achieved using inexpensive materials, a recyclable lipase, and easily applied procedures that are amenable to large-scale preparation.A variety of isopropylarenes were α-metalated with n-butylithium/potassium tert-pentoxide and treated with cyclohexene oxide to provide racemic trans-2-(1-aryl-1-methylethyl)cyclohexanols 6a-f in fair to high yield.Candida rugosa lipase and lauric acid were used to resolve these racemic alcohols by converting the (-)-enantiomer to its laurateester.The enzymatic resolutions were carried out at 40 deg C and were faster in cyclohexane than in hexanes.The synthesis and resolution of racemic trans-2-(1-methyl-1-phenylethyl)cyclohexanol (6a) were performed on a 1 mol scale in 68 percent overall yield, requiring three steps for (+)-6a and five steps for (-)-6a.