343564-56-7Relevant articles and documents
ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR
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, (2021/04/17)
Disclosed are compounds inhibiting the conversion of α–KG to D-2-HG, pharmaceutically acceptable salts, hydrates, solvates or stereoisomers thereof and pharmaceutical compositions comprising the compounds. The compound and the pharmaceutical composition c
PIPERIDINE COMPOUNDS AS PCSK9 INHIBITORS
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, (2018/11/21)
One aspect of the invention relates to a series of new PCSK9 inhibitor compounds comprising piperidine ring structures, including compounds of formula (I) and/or pharmaceutically acceptable salts thereof. Another aspect of the invention relates to methods of treating PCSK9 receptor related diseases comprising administration of one or more compounds of formula (I) or a pharmaceutically acceptable salt thereof.
Synthesis method of 3-fluoro-4-bromo-acetophenone
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Paragraph 0023; 0024; 0030; 0031; 0037; 0038, (2017/08/27)
The invention relates to a synthesis method of 3-fluoro-4-bromo-acetophenone. The method includes: taking 3-fluoro-4-bromo-benzoyl chloride, dimethylhydroxyamine hydrochloride and methylmagnesium chloride as the raw materials, carrying out aminolysis, ext