3437-30-7 Usage
Description
3,3-Dimethylpyrrolidine is an organic compound with the molecular formula C6H11NO. It is a colorless liquid with a characteristic amine-like odor. 3,3-DIMETHYLPYRROLIDINE is known for its potential applications in various industries, particularly in the pharmaceutical sector.
Uses
Used in Pharmaceutical Industry:
3,3-Dimethylpyrrolidine is used as a KRAS inhibitor for inhibiting human pancreatic adenocarcinoma cells. It plays a crucial role in the development and progression of pancreatic cancer by targeting the KRAS protein, which is a common mutation found in this type of cancer. By inhibiting the KRAS protein, 3,3-dimethylpyrrolidine can potentially slow down or stop the growth of pancreatic adenocarcinoma cells, offering a promising therapeutic approach for patients with this disease.
Check Digit Verification of cas no
The CAS Registry Mumber 3437-30-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,3 and 7 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3437-30:
(6*3)+(5*4)+(4*3)+(3*7)+(2*3)+(1*0)=77
77 % 10 = 7
So 3437-30-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H13N/c1-6(2)3-4-7-5-6/h7H,3-5H2,1-2H3
3437-30-7Relevant articles and documents
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Lehn,J.M.,Wagner,J.
, p. 4227 - 4240 (1970)
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Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates
Magee, Thomas V.,Han, Seungil,McCurdy, Sandra P.,Nguyen, Thuy-Trinh,Granskog, Karl,Marr, Eric S.,Maguire, Bruce A.,Huband, Michael D.,Chen, Jinshan Michael,Subashi, Timothy A.,Shanmugasundaram, Veerabahu
supporting information, p. 1727 - 1731 (2013/04/10)
A novel series of 3-O-carbamoyl erythromycin A derived analogs, labeled carbamolides, with activity versus resistant bacterial isolates of staphylococci (including macrolide and oxazolidinone resistant strains) and streptococci are reported. An (R)-2-aryl
