34392-85-3

Basic information

• Product Name: 2-chloro-6-methoxypyridin-3-amine
• Synonyms: 2-chloro-6-methoxypyridin-3-amine;2-Chloro-6-methoxy-3-pyridinamine;3-Amino-2-chloro-6-methoxypyridine,HCl;2-Chloro-6-methoxypyridin-3-amine, HCl;3-Pyridinamine,2-chloro-6-methoxy-;Pyridine,3-amino-2-chloro-6-methoxy- (8CI);2-Chloro-6-methoxy-pyridin-3-ylamine
• CAS NO: 34392-85-3
• Molecular Formula: C₆H₇ClN₂O
• Molecular Weight: 195.05
• EINECS: 251-989-2
• Product Categories: pharmacetical;Amines;Pyridines;C6Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;amine | alkyl chloride
• Mol File: 34392-85-3.mol
• Article Data: 8

Chemical Properties

• Melting Point: 46-50 °C
• Boiling Point: 366.6 °C at 760 mmHg
• Flash Point: 110 °C
• Appearance: /
• Density: 1.328 g/cm³
• Vapor Pressure: 1.45E-05mmHg at 25°C
• Refractive Index: 1.592
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 2-chloro-6-methoxypyridin-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-6-methoxypyridin-3-amine(34392-85-3)
• EPA Substance Registry System: 2-chloro-6-methoxypyridin-3-amine(34392-85-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 34392-85-3(Hazardous Substances Data)

Usage

General Description

2-chloro-6-methoxypyridin-3-amine is a chemical compound with the molecular formula C6H7ClN2O. It is an aromatic amine with a chlorine atom located at the 2nd position and a methoxy group at the 6th position of the pyridine ring. This chemical is used in the synthesis of pharmaceuticals and agrochemicals. It can also be used as a building block in organic chemistry to create various complex molecules. Additionally, it has potential applications in the field of medicinal chemistry as it exhibits biological activity and can be used as a starting material in drug discovery research for the development of novel therapeutics.

InChI:InChI=1/C7H7ClN2O/c1-4(11)6-3-2-5(9)7(8)10-6/h2-3H,9H2,1H3

Upstream product

• 38533-61-8 2-chloro-6-methoxy-3-nitropyridine 

Downstream Products

• 952059-64-2 6-methoxy-1,7-naphthyridin-4(1H)-one 
• 952059-61-9 4-chloro-6-methoxy-1,7-naphthyridine 
• 27017-64-7 6-methoxy-1,5-naphthyridin-2(1H)-one 
• 1352997-83-1 methyl 2-(8-(2-chloro-6-methoxypyridin-3-ylamino)octyl)-6-methoxybenzoate 
• 83732-68-7 2,3-dichloro-6-methoxypyridine 

Relevant articles and documents

COMPOUNDS TARGETING RNA-BINDING PROTEINS OR RNA-MODIFYING PROTEINS

The invention relates to a compound represented by Formula (I): or a pharmaceutically acceptable salt thereof, compositions comprising the same and methods of preparing and using the same. The variables are described herein.

Selective catalytic hydrogenation of nitro groups in the presence of activated heteroaryl halides

Chemoselective reduction of nitro groups in the presence of activated heteroaryl halides was achieved via catalytic hydrogenation with a commercially available sulfided platinum catalyst. The optimized conditions employ low temperature, pressure, and catalyst loading (0.1 mol % Pt) to afford heteroaromatic amines with minimal hydrodehalogenation byproducts.

9-Azabicyclo[3.3.1]nonane derivatives

The present invention relates to a 9-azabicyclo[3.3.1]nonane derivative of formula I, wherein each of the substituents is given the definition as set forth in the specification and claims, or a pharmaceutically acceptable salt or solvate thereof. The invention also relates to pharmaceutical compositions comprising said 9-azabicyclo[3.3.1]nonane derivatives and to their use in therapy.