344563-43-5

Basic information

• Product Name: 2-(4-tert-Butyl-cyclohexylmethyl)-3-chloro-[1,4]naphthoquinone
• CAS NO: 344563-43-5
• Molecular Weight: 344.881
• Mol File: 344563-43-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-tert-Butyl-cyclohexylmethyl)-3-chloro-[1,4]naphthoquinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-tert-Butyl-cyclohexylmethyl)-3-chloro-[1,4]naphthoquinone(344563-43-5)
• EPA Substance Registry System: 2-(4-tert-Butyl-cyclohexylmethyl)-3-chloro-[1,4]naphthoquinone(344563-43-5)

Safety Data

• Hazardous Substances Data: 344563-43-5(Hazardous Substances Data)

Downstream Products

• 88426-33-9 2-[trans-(4-t-butylcyclohexyl)methyl]-3-hydroxy-1,4-naphthoquinone 
• 86790-15-0 3-hydroxy-2-(trans-4-tert-butylcyclohexyl)methylnaphtho-1,4-quinone 

Relevant articles and documents

Buparvaquone preparation method

The invention provides a buparvaquone preparation method, which comprises: carrying out condensation, hydrolysis and decarboxylation by using o-phthalic acid diester and 2-(4-tert-butylcyclohexylmethyl)succinic acid diester as a raw material to prepare 2-[(4-tert-butylcyclohexyl)methyl]-2,3-dihydro-1,4-naphthalenedione, carrying out a substitution reaction on the 2-[(4-tert-butylcyclohexyl)methyl]-2,3-dihydro-1,4-naphthalenedione and a halogenating reagent to obtain a dihalogenated compound mixture, removing halogen hydride through an elimination reaction to obtain 2-[(4-tert-butylcyclohexyl)methyl]-3-halo-1,4-naphthalenedione, and finally carrying out a hydrolysis reaction to obtain the buparvaquone (I). According to the invention, the method has advantages of cheap and easily available raw materials, safe and simple process operation, low cost, little wastewater generation, safety and environmental protection, easily achieved reaction conditions, stable reaction intermediate, high reaction activity, high selectivity and few side reactions, and the prepared buparvaquone is few in impurity and high in purity and yield.