344768-30-5 Usage
Description
cis-1-(Phenanthrene-3-carbonyl)-piperazine-2,3-dicarboxylic Acid is a complex organic compound characterized by its unique molecular structure, which features a phenanthrene-3-carbonyl group attached to a piperazine ring with two carboxylic acid groups at the 2 and 3 positions. cis-1-(Phenanthrene-3-carbonyl)-piperazine-2,3-dicarboxylic Acid exhibits specific interactions with biological targets, making it a potential candidate for various applications in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Industry:
cis-1-(Phenanthrene-3-carbonyl)-piperazine-2,3-dicarboxylic Acid is used as an N-methyl-D-aspartate (NMDA) receptor antagonist for its ability to interact with the NR2 subunit. This application is significant in the development of treatments for neurological disorders and conditions related to the overstimulation of NMDA receptors, such as Alzheimer's disease, Parkinson's disease, and neuropathic pain.
Used in Chemical Research:
In the field of chemical research, cis-1-(Phenanthrene-3-carbonyl)-piperazine-2,3-dicarboxylic Acid can be utilized as a starting material or intermediate for the synthesis of more complex molecules with potential applications in various industries. Its unique structure and functional groups make it a valuable compound for exploring new chemical reactions and developing novel compounds with specific properties.
Check Digit Verification of cas no
The CAS Registry Mumber 344768-30-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,4,7,6 and 8 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 344768-30:
(8*3)+(7*4)+(6*4)+(5*7)+(4*6)+(3*8)+(2*3)+(1*0)=165
165 % 10 = 5
So 344768-30-5 is a valid CAS Registry Number.
344768-30-5Relevant articles and documents
Synthesis and pharmacology of N1-substituted piperazine-2,3-dicarboxylic acid derivatives acting as NMDA receptor antagonists
Morley, Richard M.,Tse, Heong-Wai,Feng, Bihua,Miller, Jacqueline C.,Monaghan, Daniel T.,Jane, David E.
, p. 2627 - 2637 (2007/10/03)
The binding site for competitive NMDA receptor antagonists is on the NR2 subunit, of which there are four types (NR2A-D). Typical antagonists such as (R)-AP5 have a subunit selectivity of NR2A > NR2B > NR2C > NR2D. The competitive NMDA receptor antagonist
