345204-05-9

Basic information

• Product Name: (2S,5R,6R)-6-{[1-(4-Amino-phenyl)-1H-[1,2,3]triazol-4-yl]-hydroxy-methyl}-3,3-dimethyl-4,4,7-trioxo-4λ⁶-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester
• CAS NO: 345204-05-9
• Molecular Weight: 587.656
• Mol File: 345204-05-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,5R,6R)-6-{[1-(4-Amino-phenyl)-1H-[1,2,3]triazol-4-yl]-hydroxy-methyl}-3,3-dimethyl-4,4,7-trioxo-4λ⁶-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5R,6R)-6-{[1-(4-Amino-phenyl)-1H-[1,2,3]triazol-4-yl]-hydroxy-methyl}-3,3-dimethyl-4,4,7-trioxo-4λ⁶-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester(345204-05-9)
• EPA Substance Registry System: (2S,5R,6R)-6-{[1-(4-Amino-phenyl)-1H-[1,2,3]triazol-4-yl]-hydroxy-methyl}-3,3-dimethyl-4,4,7-trioxo-4λ⁶-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester(345204-05-9)

Safety Data

• Hazardous Substances Data: 345204-05-9(Hazardous Substances Data)

Upstream product

• 345203-88-5 (2S,5R,6R)-6-Bromo-6-(1-hydroxy-prop-2-ynyl)-3,3-dimethyl-4,4,7-trioxo-4λ⁶-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 
• 81324-43-8 (2S,5R)-6,6-dibromo-3,3-dimethyl-4,4,7-trioxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid diphenylmethyl ester 
• 14860-64-1 4-azidoaniline 
• 345203-89-6 (2S,5R,6R)-6-(1-Hydroxy-prop-2-ynyl)-3,3-dimethyl-4,4,7-trioxo-4λ⁶-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 

Relevant articles and documents

Allyl and propargyl substituted penam sulfones as versatile intermediates toward the syntheses of new β-lactamase inhbitors

Several alkenyl derivatives were prepared using allyl penam sulfone as the key intermediate. Isomers of these derivatives having β configuration at C-6 showed potent acitivity against CcrA enzyme. A new method was developed to prepare propargyl penam sulfone. The majority of the triazoles prepared by this route exhibited good activity against all three representative enzymes used for the inhibition assay.