345252-61-1

Basic information

• Product Name: N-(1-(4-methoxyphenyl)pentyl)cyclohexanamine
• Synonyms: N-(1-(4-methoxyphenyl)pentyl)cyclohexanamine
• CAS NO: 345252-61-1
• Molecular Weight: 275.434
• Mol File: 345252-61-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(1-(4-methoxyphenyl)pentyl)cyclohexanamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-(4-methoxyphenyl)pentyl)cyclohexanamine(345252-61-1)
• EPA Substance Registry System: N-(1-(4-methoxyphenyl)pentyl)cyclohexanamine(345252-61-1)

Safety Data

• Hazardous Substances Data: 345252-61-1(Hazardous Substances Data)

Upstream product

• 693-03-8 n-butyl magnesium bromide 
• 33739-91-2 N-cyclohexyl-4-methoxybenzamide 
• 109-72-8 n-butyllithium 

Relevant articles and documents

A general method for the one-pot reductive functionalization of secondary amides

A one-pot reaction for the transformation of common secondary amides into amines with C-C bond formation is described. This method consists of in situ amide activation with Tf2O-partial reduction-addition of C-nucleophiles. The method is general in scope, which allows employing both hard nucleophiles (RMgX, RLi) and soft nucleophiles, as well as enolates. With the use of soft nucleophiles, the reaction proceeded with high chemoselectivity at a secondary amide in the presence of ester, cyano, nitro, and tertiary amide groups.