3460-29-5

Basic information

• Product Name: 4-nitro-2,5-xylidine
• Synonyms: 4-nitro-2,5-xylidine;4-Nitro-2,5-xylidine, 2-Amino-5-nitro-p-xylene;NSC 135156;NSC 43207;2,5-dimethyl-4-nitroBenzenamine
• CAS NO: 3460-29-5
• Molecular Formula: C₈H₁₀N₂O₂
• Molecular Weight: 166.1772
• EINECS: 222-405-3
• Mol File: 3460-29-5.mol
• Article Data: 9

Chemical Properties

• Melting Point: 144-146℃
• Boiling Point: 342.5 °C at 760 mmHg
• Flash Point: 160.9 °C
• Appearance: /
• Density: 1.22 g/cm³
• Vapor Pressure: 7.5E-05mmHg at 25°C
• Refractive Index: 1.601
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 1.05±0.14(Predicted)
• CAS DataBase Reference: 4-nitro-2,5-xylidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitro-2,5-xylidine(3460-29-5)
• EPA Substance Registry System: 4-nitro-2,5-xylidine(3460-29-5)

Safety Data

• Hazardous Substances Data: 3460-29-5(Hazardous Substances Data)

Usage

General Description

4-Nitro-2,5-xylidine is an organic chemical compound with the molecular formula C8H9NO2. It is a nitrosubstituted derivative of xylidine, which is used as an intermediate in the production of dyes and pigments in the textile and paper industries. 4-Nitro-2,5-xylidine is a yellow to orange crystalline solid that is insoluble in water but soluble in organic solvents. It is classified as a potential human carcinogen and is known to cause irritation to the skin, eyes, and respiratory system. Due to its hazardous properties, proper safety measures must be taken when handling and storing this chemical compound.

InChI:InChI=1/C8H10N2O2/c1-5-4-8(10(11)12)6(2)3-7(5)9/h3-4H,9H2,1-2H3

Upstream product

• 2050-44-4 N-(2,5-dimethylphenyl)acetamide 
• 95-78-3 2,5-Dimethylaniline 
• 712-32-3 1,4-Dimethyl-2,5-dinitrobenzol 
• 292852-73-4 N-(2,5-dimethylphenyl)methanesulfonamide 
• 685568-90-5 N-(2,5-dimethyl-4-nitrophenyl)methanesulfonamide 
• 6954-69-4 N-(2,5-dimethyl-4-nitrophenyl)acetamide 

Downstream Products

• 145655-61-4 2,5-Dimethyl-4-nitrophenylhydrazine 
• 15540-86-0 2-Amino-3-brom-5-nitro-p-xylol 
• 3717-94-0 N-(2,5-dimethyl-4-nitrophenyl)-4-methylbenzenesulfonamide 
• 106423-99-8 2,2′,5,5′-tetramethyl-4,4′-azodiacetanilide 
• 23410-20-0 2,5-dimethyl-4-aminoacetanilide 
• 6954-69-4 N-(2,5-dimethyl-4-nitrophenyl)acetamide 
• 55076-09-0 4,7-Dimethoxy-12,15-dinitro<2,2>paracyclophan 
• 65109-46-8 dimethyl-2,5-dinitroterephthalate 
• 65109-44-6 1,4-Bis-(dibrommethyl)-2,5-dinitro-benzol 
• 65109-45-7 2,5-dinitroterephthalic acid 
• 55119-65-8 1,4-Bis-bromomethyl-2,5-dinitro-benzene 
• 13711-13-2 2,5-dimethyl-6-chloro-4-aminophenol 
• 13711-24-5 3-chloro-2,5-dimethylaniline 
• 13711-22-3 3-chloro-2,5-dimethyl-1-nitrobenzene 

Relevant articles and documents

FORMIMIDAMIDINE COMPOUNDS USEFUL AGAINST PHYTOPATHOGENIC MICROORGANISMS

The present invention relates to 4-substituted amidine derivatives of the general formula (I), wherein A1-A4, D, L, Q, R7, R7' and integer's v and w have the meanings as defined in description. The invention further relates to methods for their preparation and use of said compounds to fight undesired phytopathogenic microorganisms, and agents for said purpose, comprising said amidine derivatives, all according to the invention. This invention further relates to a method for controlling undesired phytopathogenic microorganisms by application of said 4-substituted amidine derivatives of general formula (I) to such undesired microorganisms and/or to their habitat, according to the invention. (I)

Synthesis of ortho-phenylenebis(guanidine) derivatives with potential chirality

We report the synthesis and potential chirality of ortho-phenylenebisguanidines (BGs) with substituents at C(3) and C(6). Guanidinylation of 3,6-disubstituted benzene-1,2-diamines with 2-chloro-4,5-dihydro-1,3-dimethyl-1H-imidazolium chloride gave the corresponding BGs. X-Ray crystallography showed that the two guanidine moieties occupy different faces of the benzene ring, creating potential chirality, although optical resolution of tBu-substituted BG by chiral HPLC failed. However, a methylated acyclic bisguanidinium salt (BGms) was obtained as a chiral crystal with a space group of P212121.

Selective partial hydrogenation of dinitrobenzenes to nitroanilines catalyzed by Ru/C

Ru/C was found to be a highly effective catalyst for the selective partial hydrogenation of a range of dinitrobenzenes to their corresponding nitroanilines with excellent selectivity under mild conditions. Furthermore, the effect from other substitute groups of dinitrobenzenes on partial hydrogenation was also explored in this study. Copyright