34635-71-7Relevant articles and documents
One-pot palladium-catalyzed synthesis of selectively substituted phenanthridines by sequential aryl-aryl and heck couplings, aza-michael and retro-mannich reactions
Della Ca, Nicola,Motti, Elena,Mega, Antonio,Catellani, Marta
supporting information; experimental part, p. 1451 - 1454 (2010/08/19)
A catalytic synthesis of selectively substituted phenanthridines is achieved through a reaction sequence involving palladium/norbornene-catalyzed unsymmetrical aryl-aryl and Heck couplings followed by aza-Michael and retro-Mannich reactions. In spite of the many steps involved the method is very simple and allows the formation of selectively substituted phenanthridines under mild conditions in a straightforward one-pot reaction starting from readily available aryl iodides and bromides.