3464-63-9

Basic information

• Product Name: 9α-Hydroxy-9-hydro-16-dehydro-12-methoxyibogamine-18-carboxylic acid methyl ester
• Synonyms: 16,17-Didehydro-9,17-dihydro-9α-hydroxy-12-methoxyibogamine-18-carboxylic acid methyl ester;7-Hydroxy-1-dehydrovoacangine;9-Hydroxy-9H-voacangine;9α-Hydroxy-9-hydro-16-dehydro-12-methoxyibogamine-18-carboxylic acid methyl ester;Voacangine hydroxyindolenine
• CAS NO: 3464-63-9
• Molecular Formula: C₂₂H₂₈N₂O₄
• Molecular Weight: 0
• Mol File: 3464-63-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 529.9°C at 760 mmHg
• Flash Point: 274.3°C
• Appearance: /
• Density: 1.39g/cm³
• Vapor Pressure: 4.66E-12mmHg at 25°C
• Refractive Index: 1.673
• CAS DataBase Reference: 9α-Hydroxy-9-hydro-16-dehydro-12-methoxyibogamine-18-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 9α-Hydroxy-9-hydro-16-dehydro-12-methoxyibogamine-18-carboxylic acid methyl ester(3464-63-9)
• EPA Substance Registry System: 9α-Hydroxy-9-hydro-16-dehydro-12-methoxyibogamine-18-carboxylic acid methyl ester(3464-63-9)

Safety Data

• Hazardous Substances Data: 3464-63-9(Hazardous Substances Data)

Usage

Description

9α-Hydroxy-9-hydro-16-dehydro-12-methoxyibogamine-18-carboxylic acid methyl ester is an indole alkaloid derived from the plant Voacanga africana. Its chemical structure has been confirmed through mass spectrometry analysis. 9α-Hydroxy-9-hydro-16-dehydro-12-methoxyibogamine-18-carboxylic acid methyl ester is characterized by its unique arrangement of hydroxy, hydro, dehydro, methoxy, and carboxylic acid functional groups, which may contribute to its potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
9α-Hydroxy-9-hydro-16-dehydro-12-methoxyibogamine-18-carboxylic acid methyl ester is used as a pharmaceutical compound for its potential therapeutic properties. The presence of multiple functional groups in its structure suggests that it may interact with various biological targets, making it a candidate for the development of new drugs.
Used in Chemical Research:
In the field of chemical research, 9α-Hydroxy-9-hydro-16-dehydro-12-methoxyibogamine-18-carboxylic acid methyl ester serves as a valuable compound for studying the properties and reactivity of indole alkaloids. Its unique structure can provide insights into the synthesis and modification of related compounds, potentially leading to the discovery of new molecules with specific applications.
Used in Drug Delivery Systems:
Similar to gallotannin, 9α-Hydroxy-9-hydro-16-dehydro-12-methoxyibogamine-18-carboxylic acid methyl ester could be employed in the development of novel drug delivery systems. Its functional groups may allow for the attachment of various molecules or the formation of nanoparticles, enhancing the compound's bioavailability and therapeutic efficacy.
Used in Anticancer Applications:
Although not explicitly mentioned in the provided materials, the compound's structural features may suggest potential anticancer properties. Further research could explore its ability to modulate oncological signaling pathways or enhance the effectiveness of conventional chemotherapeutic drugs.

References

Thomas, Biemann., Tetrahedron, 24,4223 (1968)

InChI:InChI=1/C22H28N2O4/c1-4-14-9-13-11-21(20(25)28-3)18(14)24(12-13)8-7-22(26)16-10-15(27-2)5-6-17(16)23-19(21)22/h5-6,10,13-14,18,26H,4,7-9,11-12H2,1-3H3/t13-,14+,18?,21?,22?/m0/s1

Upstream product

• 510-22-5 voacangine 

Relevant articles and documents

OXYDATION D'ALCALOIDES INDOLIQES PAR L'ACIDE TRIFLUOROPERACETIQUE

The oxydation of several indolic alcaloids with trifluoroperacetic acid gives a variety of products resulting from attack at the 2(7) double bond.Tentative mechanisms are proposed.There is no hydroxylation of the aromatic nucleus.