346687-15-8

Basic information

• Product Name: diethyl 2-(4,5-difluoro-2-nitrobenzoyl)malonate
• Synonyms: diethyl 2-(4,5-difluoro-2-nitrobenzoyl)malonate
• CAS NO: 346687-15-8
• Molecular Weight: 345.257
• Mol File: 346687-15-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: diethyl 2-(4,5-difluoro-2-nitrobenzoyl)malonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-(4,5-difluoro-2-nitrobenzoyl)malonate(346687-15-8)
• EPA Substance Registry System: diethyl 2-(4,5-difluoro-2-nitrobenzoyl)malonate(346687-15-8)

Safety Data

• Hazardous Substances Data: 346687-15-8(Hazardous Substances Data)

Upstream product

• 105-53-3 diethyl malonate 
• 129951-46-8 4,5-difluoro-2-nitrobenzoyl chloride 
• 455-86-7 3,4-Difluorobenzoic acid 
• 20372-63-8 4,5-difluoro-2-nitrobenzoic acid 

Downstream Products

• 127451-97-2 ethyl 3,4-difluoro-2-nitrobenzoylacetate 

Relevant articles and documents

Synthesis of 4-Hydroxyquinolin-2(1H)-one analogues and 2-substituted quinolone derivatives

A versatile synthetic method for preparing 4-hydroxyquinolone and 2-substituted quinolone compounds from simple benzoic acid derivatives was demonstrated. The synthetic strategies involve the use of well known ethyl acetoacetate synthesis, malonic ester s

Synthesis and antibacterial activity of 2-substituted 6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids

A series of 2-substituted 6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids was prepared and evaluated for antibacterial activity. The 6-fluoro-2-methyl-1-prenyl-1,4-dihydro-7-(3,5-dimethylpiperazinyl)-4-oxo-3-quinolinecarboxylic acid (14f) exhibited