346721-91-3

Basic information

• Product Name: (3-BROMOBENZOYL)PYRROLIDINE
• Synonyms: Methanone, (3-bromophenyl)-1-pyrrolidinyl-
• CAS NO: 346721-91-3
• Molecular Formula: C₁₁H₁₂BrNO
• Molecular Weight: 254.13
• Mol File: 346721-91-3.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 366.0±25.0 °C(Predicted)
• Appearance: /
• Density: 1.469±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -1.90±0.20(Predicted)
• CAS DataBase Reference: (3-BROMOBENZOYL)PYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (3-BROMOBENZOYL)PYRROLIDINE(346721-91-3)
• EPA Substance Registry System: (3-BROMOBENZOYL)PYRROLIDINE(346721-91-3)

Safety Data

• Hazardous Substances Data: 346721-91-3(Hazardous Substances Data)

Usage

General Description

"(3-Bromobenzoyl)pyrrolidine" is a synthetic organic compound with the molecular formula C11H12BrNO. It belongs to a class of organic compounds known as benzoylpyrrolidines. As its name suggests, it consists of a pyrrolidine ring (a five-membered nitrogenous ring) attached to a 3-bromobenzoyl group (a phenyl ring substituted with a bromine atom and an acyl group). The chemical is often used in research settings, particularly in synthetic organic chemistry. Although primarily used as an intermediate in organic synthesis, details regarding the specific applications or potential hazards of (3-Bromobenzoyl)pyrrolidine are limited. It is generally white to off-white in appearance and should be handled with typical safety measures for laboratory chemicals such as wearing gloves, eye protection, and adequate clothing.

Upstream product

• 123-75-1 pyrrolidine 
• 585-76-2 m-bromobenzoic acid 
• 3132-99-8 m-bromobenzoic aldehyde 
• 1711-09-7 3-bromobenzoyl chloride 

Downstream Products

• 1373312-54-9 C₂₅H₂₅BrN₂O₃S 
• 936092-82-9 [3-(2-chloro-5-methyl-pyrimidin-4-ylamino)phenyl]-pyrrolidin-1-yl-methanone 
• 168820-15-3 1-(3-bromobenzyl)pyrrolidine 
• 99586-31-9 2‐(3‐bromophenyl)benzo[d]oxazole 
• 1225279-04-8 (pyrrolidin-1-yl)[3-(quinoxalin-6-yl)phenyl]methanone 
• 1225279-03-7 6-{3-[1-methyl-1-(pyrrolidin-1-yl)ethyl]phenyl}quinoxaline 

Relevant articles and documents

Visible-Light-Mediated Oxidative Amidation of Aldehydes by Using Magnetic CdS Quantum Dots as a Photocatalyst

A magnetic CdS quantum dot (Fe3O4/polydopamine (PDA)/CdS) was synthesized through a facile and convenient method from inexpensive starting materials. Characterization of the prepared catalyst was performed by means of FTIR spectrosco

A practical catalytic reductive amination of carboxylic acids

We report reductive alkylation reactions of amines using carboxylic acids as nominal electrophiles. The two-step reaction exploits the dual reactivity of phenylsilane and involves a silane-mediated amidation followed by a Zn(OAc)2-catalyzed amide reduction. The reaction is applicable to a wide range of amines and carboxylic acids and has been demonstrated on a large scale (305 mmol of amine). The rate differential between the reduction of tertiary and secondary amide intermediates is exemplified in a convergent synthesis of the antiretroviral medicine maraviroc. Mechanistic studies demonstrate that a residual 0.5 equivalents of carboxylic acid from the amidation step is responsible for the generation of silane reductants with augmented reactivity, which allow secondary amides, previously unreactive in zinc/phenylsilane systems, to be reduced.

One-Pot Tandem Photoredox and Cross-Coupling Catalysis with a Single Palladium Carbodicarbene Complex

The combination of conventional transition-metal-catalyzed coupling (2 e? process) and photoredox catalysis (1 e? process) has emerged as a powerful approach to catalyze difficult cross-coupling reactions under mild reaction conditions. Reported is a palladium carbodicarbene (CDC) complex that mediates both a Suzuki–Miyaura coupling and photoredox catalysis for C?N bond formation upon visible-light irradiation. These two catalytic pathways can be combined to promote both conventional transition-metal-catalyzed coupling and photoredox catalysis to mediate C?H arylation under ambient conditions with a single catalyst in an efficient one-pot process.