3470-38-0

Basic information

• Product Name: (1E)-1,3-bis(4-bromophenyl)triaz-1-ene
• Synonyms: 1-triazene, 1,3-bis(4-bromophenyl)-, (1E)-
• CAS NO: 3470-38-0
• Molecular Formula: C₁₂H₉Br₂N₃
• Molecular Weight: 355.028
• Mol File: 3470-38-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 399.9°C at 760 mmHg
• Flash Point: 195.6°C
• Density: 1.7g/cm³
• Vapor Pressure: 1.32E-06mmHg at 25°C
• Refractive Index: 1.662
• CAS DataBase Reference: (1E)-1,3-bis(4-bromophenyl)triaz-1-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (1E)-1,3-bis(4-bromophenyl)triaz-1-ene(3470-38-0)
• EPA Substance Registry System: (1E)-1,3-bis(4-bromophenyl)triaz-1-ene(3470-38-0)

Safety Data

• Hazardous Substances Data: 3470-38-0(Hazardous Substances Data)

Usage

Description

(1E)-1,3-bis(4-bromophenyl)triaz-1-ene, a member of the triazene family, is a chemical compound with the molecular formula C18H11Br2N3. It features two 4-bromophenyl groups linked by a triazene functional group, giving it a distinctive yellow solid appearance. (1E)-1,3-bis(4-bromophenyl)triaz-1-ene is widely recognized for its applications in organic synthesis and material science research, where its unique structure and properties contribute to the development of innovative compounds and materials.

Uses

Used in Organic Synthesis:
(1E)-1,3-bis(4-bromophenyl)triaz-1-ene is utilized as a key intermediate in organic synthesis for the creation of various complex organic molecules. Its presence in reactions can facilitate the formation of desired products, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Material Science Research:
In the field of material science, (1E)-1,3-bis(4-bromophenyl)triaz-1-ene is employed as a building block for the development of new materials. Its structural attributes allow it to be integrated into the design of advanced materials with specific properties, such as those with potential applications in electronics, photonics, or as high-performance polymers.
Used in Pharmaceutical Research:
(1E)-1,3-bis(4-bromophenyl)triaz-1-ene is also being explored for its potential pharmacological properties. Researchers are investigating its capacity to serve as a drug candidate, given its unique chemical structure that may interact with biological targets in novel ways, potentially leading to the discovery of new therapeutic agents.
Used in Drug Development:
As a compound with potential medicinal applications, (1E)-1,3-bis(4-bromophenyl)triaz-1-ene is used in drug development to identify and optimize new chemical entities. Its properties may be harnessed to design drugs with improved efficacy, selectivity, and safety profiles, contributing to advancements in medicinal chemistry and pharmacology.

Upstream product

• 64-17-5 ethanol 
• 106-40-1 4-bromo-aniline 
• 7647-01-0 hydrogenchloride 
• 2028-85-5 (4-bromophenyl)diazonium chloride 
• 673-40-5 4-bromobenzenediazonium tetrafluoroborate 
• 127-06-0 acetone oxime 
• 100-34-5 benzene diazonium chloride 

Downstream Products

• 42035-08-5 1,3-bis-(4-bromo-phenyl)-3-methyl-triazene 
• 2028-85-5 (4-bromophenyl)diazonium chloride 
• 57965-33-0 4-bromo-benzenediazonium; iodide 
• 2028-82-2 4-bromophenyldiazonium bromide 
• 15630-29-2 trans-bis[1,3-(4-bromophenyl)triazenide] mercury(II) 
• 34855-33-9 4-bromo-N-(4-bromophenyl)benzamide 

Relevant articles and documents

Diaryl triazenes inhibit cytochrome P450 1A1 and 1B1 more strongly than aryl morpholino triazenes

Several diaryl triazene derivatives were synthesized and tested for their ability to inhibit cytochrome P450 1A1 and 1B1 as a potential means to prevent and treat cancer. These compounds are more planar than their conformational flexible aryl morpholino t

Novel one-pot synthesis of thiophenols from related triazenes under mild conditions

In this work, at first, triazenes were synthesized from primary aryl amines. Afterwards, triazenes were converted into the corresponding thiophenols in one-pot using sodium sulfide in acidic media, by in situ generation of diazonium counterion beside hydrogen sulfide as anionic sulfur nucleophile at room temperature. The procedure can be a convenient shortcut for the preparation of thiophenols from primary aryl amines. Georg Thieme Verlag Stuttgart · New York.

Nitrosation with Sodium Hexanitrocobaltate(III)

Na3Co(NO2)6 has been investigated as a new reagent for the nitrosation of various substrates containing an amino functionality. Reactions took place in an aqueous solution of the reagent. The pH of the reaction mixture remained in the range 4.3-5. Thus, hydrazides were transformed to the corresponding acyl azides, and the reactions with arenesulfonyl hydrazines afforded arenesulfonyl azides. Treatment of aromatic amines with Na3Co(NO2)6 gave 1,3-diaryltriazenes in excellent yields; coupling of the initially formed diazo compound to the electron rich aromatic ring was also observed. Nitrosation of aliphatic amines was not possible due to complex formation with the reagent.