347146-31-0

Basic information

• Product Name: 6-(4-Toluenesulfonylamino) isoquinoline
• Synonyms: 6-(4-Toluenesulfonylamino) isoquinoline
• CAS NO: 347146-31-0
• Molecular Weight: 298.365
• Mol File: 347146-31-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 6-(4-Toluenesulfonylamino) isoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(4-Toluenesulfonylamino) isoquinoline(347146-31-0)
• EPA Substance Registry System: 6-(4-Toluenesulfonylamino) isoquinoline(347146-31-0)

Safety Data

• Hazardous Substances Data: 347146-31-0(Hazardous Substances Data)

Upstream product

• 23687-26-5 6-isoquinolinamine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 347146-33-2 6-amino-1-chloroisoquinoline 

Relevant articles and documents

PHARMACEUTICALLY ACTIVE PYRAZOLO-TRIAZINE AND/OR PYRAZOLO-PYRIMIDINE DERIVATIVES

The present invention relates to pyrazolo [1,5 -a] [1,3,5 ]triazine and pyrazolo[1,5-a] pyrimidine derivatives and/or pharmaceutically acceptable salts thereof, the use of these derivatives as pharmaceutically active agents, especially for the prophylaxis and/or treatment of cell proliferative diseases, inflammatory diseases, immunological diseases, cardiovascular diseases and infectious diseases. Furthermore, the present invention is directed towards pharmaceutical compositions containing at least one of the pyrazo lo [1,5-a][1,3,5 ]triazine and pyrazolo [1,5-a]pyrimidine derivatives and/or pharmaceutically acceptable salts thereof.

Sulfonamide-containing heterocyclic compounds

The present invention provides a sulfonamide- or sulfonylurea-containing heterocyclic compounds. Specifically, it provides a heterocyclic compound represented by the formula (I), a pharmacologically acceptable salt thereof or a hydrate of them. In the formula, A is hydrogen atom, a halogen atom, a C1-C4 alkyl or alkoxy group which may be substituted with a halogen atom, or cyano group; B is an optionally substituted aryl group or monocyclic heteroaryl group, or: (wherein, the ring Q is an aromatic ring which may have nitrogen atom; and the ring M is a ring sharing a double bond with the ring Q, which ring may have a heteroatom; and the rings Q and M may share nitrogen atom); K is a single bond; T, W, X and Y are the same as or different from each other and each is ═C(D)— (wherein, D is hydrogen or a halogen atom) or nitrogen atom; U and V are the same as or different from each other and each is ═C(D)—, nitrogen atom, —CH2—, oxygen atom or —CO—; Z is a single bond or —CO—NH—; and R1 is hydrogen atom, etc.