34761-15-4

Basic information

• Product Name: 2-Benzoyl-1-benzothiophen-3-amine
• Synonyms: 2-Benzoyl-1-benzothiophen-3-amine
• CAS NO: 34761-15-4
• Molecular Weight: 253.324
• Mol File: 34761-15-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Benzoyl-1-benzothiophen-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzoyl-1-benzothiophen-3-amine(34761-15-4)
• EPA Substance Registry System: 2-Benzoyl-1-benzothiophen-3-amine(34761-15-4)

Safety Data

• Hazardous Substances Data: 34761-15-4(Hazardous Substances Data)

Upstream product

• 63216-04-6 o-benzyl mercapto-benzonitrile 
• 394-47-8 2-fluorobenzonitrile 
• 34761-11-0 2-cyanothiophenol 
• 70-11-1 α-bromoacetophenone 

Relevant articles and documents

Synthesis and analgesic activity of some 1-benzofurans, 1-benzothiophenes and indoles

3-Unsubstituted 1-benzofurans 1e and 1f, 3-methyl-1-benzofurans 1a-1d, and 3-amino-1-benzofurans 2a-21, as well as 3-amino-1-benzothiophenes 3a, 3b and 3-aminoindoles 4a-4f, 11a, and 11b were prepared and tested as analgesics. The 3-amino-1-benzofurans 2 were prepared from the corresponding 2-hydroxybenzonitriles 5 and phenacyl bromides 6 via intermediates 7. Similar treatment of 2-sulfanylbenzonitrile (8) provided 3-amino-1-benzothiophenes 3. Appropriately substituted 2-aminobenzonitriles 9 then provided N-substituted 3-aminoindoles 4. 1-(Ethoxycarbonyl)indoles 4e and 4f were successfully deprotected giving indoles 11a and 11b, respectively.