34773-51-8

Basic information

• Product Name: 1-(5-bromothiophen-2-yl)-2,2,2-trifluoroethanone
• Synonyms: 1-(5-bromothiophen-2-yl)-2,2,2-trifluoroethanone;1-(5-bromothiophen-2-yl)-2,2,2-trifluoroethan-1-one
• CAS NO: 34773-51-8
• Molecular Formula: C₆H₂BrF₃OS
• Molecular Weight: 259.0436896
• Mol File: 34773-51-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 254.6 °C at 760 mmHg
• Flash Point: 107.8 °C
• Appearance: /
• Density: 1.811 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(5-bromothiophen-2-yl)-2,2,2-trifluoroethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-bromothiophen-2-yl)-2,2,2-trifluoroethanone(34773-51-8)
• EPA Substance Registry System: 1-(5-bromothiophen-2-yl)-2,2,2-trifluoroethanone(34773-51-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 34773-51-8(Hazardous Substances Data)

Usage

General Description

1-(5-bromothiophen-2-yl)-2,2,2-trifluoroethanone is a chemical compound that contains a bromothiophene group and a trifluoroethanone group. It is a ketone with a molecular formula of C8H4BrF3OS. 1-(5-bromothiophen-2-yl)-2,2,2-trifluoroethanone is used as a building block in organic synthesis and medicinal chemistry. It has potential applications in pharmaceutical research, agrochemicals, and materials science. The presence of the bromine and fluorine atoms in the molecule gives it unique properties and reactivity, making it useful for creating diverse compounds with specific characteristics. Due to its functional groups, 1-(5-bromothiophen-2-yl)-2,2,2-trifluoroethanone has potential applications in various industries and research fields.

Upstream product

• 3141-27-3 2,5-dibromothiophen 
• 104863-67-4 N-methoxy-N-methyltrifluoroacetamide 
• 4701-17-1 5-bromo-2-thiophencarboxaldehyde 
• 1236066-84-4 5-bromo-N-methoxy-N-methylthiophene-2-carboxamide 
• 31555-60-9 5-bromothiophene-2-carbonyl chloride 
• 35304-69-9 1-(5-bromothiophen-2-yl)-2,2,2-trifluoroethanol 

Downstream Products

• 35304-69-9 1-(5-bromothiophen-2-yl)-2,2,2-trifluoroethanol 
• 34773-49-4 2,2,2-trifluoro-1-(5-phenylthiophen-2-yl)ethanone 

Relevant articles and documents

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A series of electron-accepting π-conjugated molecules having fluorine-containing dicyanovinylidene as terminal groups has been synthesized for the application to electron-transporting semiconductors. This terminal group can be easily incorporated into π-conjugated frameworks. Electrochemical measurements indicated that these compounds showed low-lying lowest unoccupied molecular orbital energy levels, which could be fine-tuned by the combination of central unit. The thin films fabricated by solution process showed typical electron-transporting characteristics in field-effect transistors.

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5-Aryl-2-(trifluoroacetyl)thiophenes were identified as a new series of class II HDAC inhibitors (HDACi). Further development of this new series led to compounds such as 6h, a potent inhibitor of HDAC4 and HDAC6 (HDAC4 WT IC 50 = 310 nM, HDAC6