348626-49-3

Basic information

• Product Name: (5R)-5-(hydroxymethyl)-3-[4-(2-oxopyrrolidin-1-yl)phenyl]-1,3-oxazolidin-2-one
• Synonyms: (5R)-5-(hydroxymethyl)-3-[4-(2-oxopyrrolidin-1-yl)phenyl]-1,3-oxazolidin-2-one
• CAS NO: 348626-49-3
• Molecular Weight: 276.292
• Mol File: 348626-49-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (5R)-5-(hydroxymethyl)-3-[4-(2-oxopyrrolidin-1-yl)phenyl]-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5R)-5-(hydroxymethyl)-3-[4-(2-oxopyrrolidin-1-yl)phenyl]-1,3-oxazolidin-2-one(348626-49-3)
• EPA Substance Registry System: (5R)-5-(hydroxymethyl)-3-[4-(2-oxopyrrolidin-1-yl)phenyl]-1,3-oxazolidin-2-one(348626-49-3)

Safety Data

• Hazardous Substances Data: 348626-49-3(Hazardous Substances Data)

Upstream product

• 348626-48-2 benzyl [4-(2-oxopyrrolidin-1-yl)phenyl]carbamate 
• 60456-26-0 (R)-glycidyl butyrate 
• 123-51-3 i-Amyl alcohol 
• 13691-22-0 1-(4-aminophenyl)pyrrolidin-2-one 

Downstream Products

• 348626-50-6 (5S)-5-(aminomethyl)-3-[4-(2-oxopyrrolidin-1-yl)phenyl]-1,3-oxazolidin-2-one 

Relevant articles and documents

COMBINATION THERAPY OF SUBSTITUTED OXAZOLIDINONES

The present invention relates to combinations of A) oxazolidinones of the formula (I) with B) acetylsalicylic acid (aspirin) and C) an ADP receptor antagonist, in particular P2Y12 purinoreceptor blocker, to a process for producing these combinations and to the use thereof as medicaments, in particular for the prophylaxis and/or treatment of thromboembolic disorders.

Combination Therapy Comprising Substituted Oxazolidinones for the Prevention and Treatment of Cerebral Circulatory Disorders

The present invention relates to combinations of A) oxazolidinones of the formula (I), with B) antiarrhythmics, processes for the production of these combinations, their use for the prophylaxis and/or treatment of diseases, and their use for the manufacture of medicaments for the prophylaxis and/or treatment of diseases, especially of thromboembolic disorders and/or complications.

Substituted oxazolidinones and their in the field of blood coagulation

The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.