34929-31-2Relevant articles and documents
Copper-catalyzed oxidative coupling of carboxylic acids with formamides for the synthesis of α,β-unsaturated amides
Li, Huamin,Pan, Changduo,Cheng, Yixiang,Zhu, Chengjian
, p. 6679 - 6681 (2013)
A novel and efficient protocol for the synthesis of α,β- unsaturated amides has been developed using catalytic amount of Cu(OAc) 2 and TBHP as an available oxidant. Oxidative coupling of various unsaturated carboxylic acids with N,N-disubstituted formamides was examined to furnish the desired products in good yields.
Condensation of aromatic aldehydes with VyV-dimethylacetamide in presence of dialkyl carbonates as dehydrating agents
Weidlich, Tomas,Prokes, Lubomir,Ruzicka, Ales,Padelkova, Zdenka
experimental part, p. 205 - 211 (2010/08/22)
Reactions of benzaldehydes with excess N,N- dimethylacetamide at 140 °C in the presence of diethyl carbonate as dehydrating agent and a base gave (E)-N,N- dimethylcinnamamides in good yields. If hydroxybenzal- dehydes are used as substrates the reaction is accompanied by alkylation. Springer-Verlag 2010.
