349446-90-8

Basic information

• Product Name: 1,1,3-Propanetricarboxylic acid, 2-(4-fluorophenyl)-, trimethyl ester
• CAS NO: 349446-90-8
• Molecular Formula: C15H17FO6
• Molecular Weight: 312.295
• Mol File: 349446-90-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,1,3-Propanetricarboxylic acid, 2-(4-fluorophenyl)-, trimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,3-Propanetricarboxylic acid, 2-(4-fluorophenyl)-, trimethyl ester(349446-90-8)
• EPA Substance Registry System: 1,1,3-Propanetricarboxylic acid, 2-(4-fluorophenyl)-, trimethyl ester(349446-90-8)

Safety Data

• Hazardous Substances Data: 349446-90-8(Hazardous Substances Data)

Upstream product

• 96426-60-7 methyl (2E)-3-(4-fluorophenyl)-2-propenoate 
• 108-59-8 malonic acid dimethyl ester 
• 459-32-5 4-fluorocinnamic acid 
• 100891-10-9 methyl p-fluorocinnamate 

Downstream Products

• 349446-97-5 Methanesulfonic acid (3S,4R)-4-(4-fluoro-phenyl)-1-((S)-1-phenyl-ethyl)-piperidin-3-ylmethyl ester 
• 349446-95-3 (3S,4R,1'S)-4-(4-fluorophenyl)-3-methoxycarbonyl-1-(1'-phenylethyl)piperidin-2-one 
• 349446-91-9 (3S,1'S)-3-(4-fluorophenyl)-5-oxo-5-(1'-phenylethylamino)pentanoic acid 
• 349446-93-1 (3S)-5-bromo-3-(4-fluorophenyl)pentanoic acid (1S)-1-phenylethylamide 
• 349446-92-0 (3R)-3-(4-fluorophenyl)-5-hydroxypentanoic acid (1S)-1-phenylethylamide 
• 349446-96-4 {(3S,4R)-4-(p-fluorophenyl)-3-(hydroxymethyl)-1-[1-(S)-phenylethyl]}piperidine 
• 349446-94-2 (4R,1'S)-4-(4-fluorophenyl)-1-(1'-phenylethyl)piperidin-2-one 
• 3449-63-6 3-(4-fluorophenyl)pentan-1,5-dioic acid 

Relevant articles and documents

BENZO-FUSED 5-MEMBERED HETROCYCLE COMPOUNDS,PROCESS FOR PREPARATION OF THE SAME, AND USE THEREOF

A compound represented by the formula: (wherein, R1 and R2 are the same or different and each represents a hydrogen atom, hydrocarbon group or heterocyclic group, or R1 and R2 may form, together with the adjacent carbon atom, a 3-8 membered iso- or heterocyclic group, R3 represents a cyclic group, a hydroxy group, a mercapto group that may have oxo, or an amino group, R4 represents a hydrogen atom, a hydrocarbon group, a hydroxy group, a mercapto group which may have oxo, or an amino group, or R2 and R4 may link together to form a double bond, X represents a bond or a linear hydrocarbon group, W represents an oxygen atom or a sulfur atom, ring B represents a 5-8 membered nitrogen-containing heterocyclic group, ring C represents a benzene ring, and --- represents a single bond or a double bond), or a salt or a prodrug thereof that has excellent neurodegenerative inhibitory activity and brain penetrability, and is useful as an agent for preventing/treating neurodegenerative diseases.