34956-31-5

Basic information

• Product Name: Acetamide,N-(4-acetyl-3-methylphenyl)-
• Synonyms: m-Acetotoluidide,4'-acetyl- (6CI)
• CAS NO: 34956-31-5
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.23
• Product Categories: Aromatic Acetophenones & Derivatives (substituted)
• Mol File: 34956-31-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 137-140 °C(lit.)
• Boiling Point: 384.475 °C at 760 mmHg
• Flash Point: 166.507 °C
• Appearance: /
• Density: 1.123 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 14.60±0.70(Predicted)
• CAS DataBase Reference: Acetamide,N-(4-acetyl-3-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide,N-(4-acetyl-3-methylphenyl)-(34956-31-5)
• EPA Substance Registry System: Acetamide,N-(4-acetyl-3-methylphenyl)-(34956-31-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37
• WGK Germany: 3
• Hazardous Substances Data: 34956-31-5(Hazardous Substances Data)

Usage

Description

Acetamide,N-(4-acetyl-3-methylphenyl)-, also known as 4′-Acetamido-2′-methylacetophenone, is an organic compound derived from acetanilides. It is synthesized by treating m-methylacetanilide with acetyl chloride in the presence of aluminum chloride in carbon disulfide. Acetamide,N-(4-acetyl-3-methylphenyl)serves as a key intermediate in the chemical synthesis process.

Uses

Used in Chemical Synthesis:
Acetamide,N-(4-acetyl-3-methylphenyl)is used as an intermediate in the preparation of 4-amino-2-methylacetophenone by acid hydrolysis. This transformation is crucial for the production of various chemical compounds and materials that have applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Acetamide,N-(4-acetyl-3-methylphenyl)may be utilized as a building block for the synthesis of various pharmaceutical compounds. Its ability to be converted into 4-amino-2-methylacetophenone makes it a valuable precursor for the development of new drugs with potential therapeutic applications.
Used in Dye and Pigment Industry:
Acetamide,N-(4-acetyl-3-methylphenyl)may also find applications in the dye and pigment industry, where it can be used to synthesize colorants and dyes for various applications, such as in the textile, plastics, and printing industries.
Used in Research and Development:
Acetamide,N-(4-acetyl-3-methylphenyl)is used as a research compound in the development of new chemical processes and methodologies. Its unique structure and reactivity make it an interesting candidate for exploring novel synthetic routes and understanding the underlying chemical reactions.

Upstream product

• 75-36-5 acetyl chloride 
• 537-92-8 3-Methylacetanilide 

Downstream Products

• 34956-30-4 N-(3-methyl-4-(2-(4-morpholinyl)-2-thioxoethyl)phenyl)acetamide 
• 34841-55-9 2-(4-amino-2-methylphenyl)acetic acid 
• 1076188-17-4 (E)-1-(4-amino-2-methylphenyl)-3-(4-hydroxy-3-methylphenyl)prop-2-en-1-one 
• 1076188-42-5 (E)-N-(4-(3-(4-hydroxy-3-methylphenyl)acryloyl)-3-methylphenyl)acetamide 
• 1086626-76-7 (E)-1-(4-amino-2-methylphenyl)-3-(3-methyl-1H-indazol-5-yl)prop-2-en-1-one 
• 98-86-2 acetophenone 
• 38177-98-9 2-methyl-4-aminoacetophenone 

Relevant articles and documents

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Doxepin analogs and methods of use thereof

The invention relates to novel antihistamines and methods of modulating sleep by administering a doxepin analog or a pharmaceutically effective salt thereof.