34974-00-0Relevant articles and documents
Structure-activity studies of pyridinylalkyl-isocytosine H1-receptor antihistamines and identification of an active conformation
Cooper,Durant,Ganellin,Ife,Meeson,Sach
, p. 3 - 19 (2007/10/02)
-
5-(HYDROXYPYRIDYLALKYL)-4-PYRIMIDONES
-
, (2008/06/13)
The compounds are substituted 2-amino-4-pyrimidones with a 5-(hydroxypyridylalkyl) substituent which are histamine H 2-antagonists. Two specific compounds are 2-2-(3-bromo-2-pyridylmethylthio) ethylamino!-5-(2-hydroxy-4-pyridylmethyl)-4-pyrimidone and 2-4-(3-methoxy-2-pyridyl)butylamino!-5-(2-hydroxy-4-pyridylmethyl)-4-pyrimido ne.