350-98-1

Basic information

• Product Name: Benzamide, N-[4-(trifluoromethyl)phenyl]-
• CAS NO: 350-98-1
• Molecular Formula: C14H10F3NO
• Molecular Weight: 265.235
• Mol File: 350-98-1.mol
• Article Data: 53

Chemical Properties

• CAS DataBase Reference: Benzamide, N-[4-(trifluoromethyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-[4-(trifluoromethyl)phenyl]-(350-98-1)
• EPA Substance Registry System: Benzamide, N-[4-(trifluoromethyl)phenyl]-(350-98-1)

Safety Data

• Hazardous Substances Data: 350-98-1(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 139032-23-8 1-isocyano-4-(trifluoromethyl)benzene 
• 2446-51-7 N-methoxybenzamide 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 98-08-8 α,α,α-trifluorotoluene 
• 100-47-0 benzonitrile 
• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 
• 99-94-5 p-Toluic acid 
• 455-14-1 4-trifluoromethylphenylamine 
• 350-42-5 4-methylbenzoyl fluoride 
• 1934-92-5 N-methyl-N-phenyl-benzamide 
• 495-18-1 Benzohydroxamic acid 
• 61650-22-4 N-(pivaloyloxy)benzamide 
• 455-13-0 4-Iodobenzotrifluoride 

Downstream Products

• 7472-54-0 N-(p-methoxyphenyl)benzamide 
• 22864-65-9 N-methyl-4-(trifluoromethyl)aniline 
• 100-51-6 benzyl alcohol 
• 343617-78-7 N-(4-(trifluoromethyl)phenyl)benzothioamide 
• 1620817-48-2 2-phenyl-6-(trifluoromethyl)benzo[d]oxazole 
• 1446786-09-9 2,4-diphenyl-6-(trifluoromethyl)quinazoline 
• 1609460-36-7 N-benzyl-N′-(4-(trifluoromethyl)phenyl)benzimidamide 
• 1305221-98-0 N-phenyl-N-4-trifluoromethylphenylbenzamide 
• 188122-52-3 (E)-2-hexenyl N-[4-(trifluoromethyl)phenyl]benzimidate 
• 206360-82-9 N-(4-Trifluoromethyl-phenyl)-benzimidic acid (Z)-hex-2-enyl ester 
• 206360-81-8 N-(4-Trifluoromethyl-phenyl)-benzimidic acid (E)-4-methyl-pent-2-enyl ester 
• 206360-79-4 N-(4-Trifluoromethyl-phenyl)-benzimidic acid (E)-hex-2-enyl ester 
• 425366-09-2 N-(4-trifluoromethyl-phenyl)-benzimidic acid 4-cyano-phenyl ester 
• 425366-22-9 phenylmethylidyne-(4-trifluoromethyl-phenyl)-ammonium 

Relevant articles and documents

Visible-Light Carbon Nitride-Catalyzed Aerobic Cyclization of Thiobenzanilides under Ambient Air Conditions

A metal-free heterogeneous photocatalysis has been developed for the synthesis of benzothiazoles via intramolecular C-H functionalization/C-S bond formation of thiobenzanilides by inexpensive graphitic carbon nitride (g-C3N4) under visible-light irradiation. This reaction provides access to a broad range of 2-substituted benzothiazoles in high yields under an air atmosphere at room temperature without addition of a strong base or organic oxidizing reagents. In addition, the catalyst was found to be stable and reusable after five reaction cycles.

Acetonitrile and benzonitrile as versatile amino sources in copper-catalyzed mild electrochemical C-H amidation reactions

A mild, efficient electrochemical approach to the site-selective direct C-H amidation of benzene and its derivatives with acetonitrile and benzonitrile has been developed. It has been shown that joint electrochemical oxidation of various arenes in the presence of a copper salt as a catalyst and nitriles leads to the formation of N-phenylacetamide from benzene and N-benzylacetamides from benzyl derivatives (up to 78% yield). A favorable feature of the process is mild conditions (room temperature, ambient pressure, no strong oxidants) that meet the criteria of green chemistry.

Carboxylic Acid Deoxyfluorination and One-Pot Amide Bond Formation Using Pentafluoropyridine (PFP)

This work describes the application of pentafluoropyridine (PFP), a cheap commercially available reagent, in the deoxyfluorination of carboxylic acids to acyl fluorides. The acyl fluorides can be formed from a range of acids under mild conditions. We also demonstrate that PFP can be utilized in a one-pot amide bond formation via in situ generation of acyl fluorides. This one-pot deoxyfluorination amide bond-forming reaction gives ready access to amides in yields of ≤94%.