350797-54-5 Usage
Description
1-(3-benzoyloxypropyl)-5-(2-nitropropyl)-2,3-dihydroindole is a complex chemical compound characterized by its unique structure, which includes a benzoyloxypropyl group, a nitropropyl group, and a dihydroindole core. 1-(3-benzoyloxypropyl)-5-(2-nitropropyl)-2,3-dihydroindole features a benzoyloxy derivative of propyl, a nitro functional group attached to a propyl chain, and a bicyclic structure akin to the indole nucleus, a common motif in biologically active compounds. Its potential pharmaceutical or industrial applications are currently under investigation, with further research required to ascertain its specific properties and uses.
Uses
Used in Pharmaceutical Applications:
1-(3-benzoyloxypropyl)-5-(2-nitropropyl)-2,3-dihydroindole is used as a potential pharmaceutical agent for [application reason] due to its complex structure and the presence of biologically active motifs. 1-(3-benzoyloxypropyl)-5-(2-nitropropyl)-2,3-dihydroindole's specific properties and potential therapeutic applications are still under investigation.
Used in Chemical Research:
In the field of chemical research, 1-(3-benzoyloxypropyl)-5-(2-nitropropyl)-2,3-dihydroindole is used as a subject of study for [application reason], such as understanding its reactivity, stability, and potential interactions with other molecules. This research could lead to the discovery of new applications in various industries.
Used in Material Science:
1-(3-benzoyloxypropyl)-5-(2-nitropropyl)-2,3-dihydroindole may be used as a component in the development of new materials for [application reason], such as its potential to influence the properties of polymers or contribute to the creation of novel composites. Further research is needed to explore these possibilities.
Check Digit Verification of cas no
The CAS Registry Mumber 350797-54-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,0,7,9 and 7 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 350797-54:
(8*3)+(7*5)+(6*0)+(5*7)+(4*9)+(3*7)+(2*5)+(1*4)=165
165 % 10 = 5
So 350797-54-5 is a valid CAS Registry Number.
350797-54-5Relevant articles and documents
Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α1A-Adrenoceptor Antagonists
Zhao, Fei,Li, Jing,Chen, Ying,Tian, Yanxin,Wu, Chenglin,Xie, Yanan,Zhou, Yu,Wang, Jiang,Xie, Xin,Liu, Hong
, p. 3826 - 3839 (2016/05/24)
A series of indoline and indole derivatives were designed, synthesized, and evaluated as selective α1A-adrenergic receptor (α1A-AR) antagonists for the treatment of benign prostatic hyperplasia (BPH). In this study, two highly selective and potent α1A-AR antagonists, compounds (R)-14r (IC50 = 2.7 nM, α1B/α1A = 640.1, α1D/α1A = 408.2) and (R)-23l (IC50 = 1.9 nM, α1B/α1A = 1506, α1D/α1A = 249.6), which exhibited similar activities and better selectivities in cell-based calcium assays as compared with the marketed drug silodosin (IC50 = 1.9 nM, α1B/α1A = 285.9, α1D/α1A = 14.4), were identified. In the functional assays with isolated rat tissues, compounds (R)-14r and (R)-23l also showed high potency and uroselectivity. Most importantly, (R)-14r and (R)-23l can significantly decrease the micturition frequency and increase the mean voided volume of the BPH rats in a dose-dependent manner, making them worthy of further investigation for the development of anti-BPH agents.
NOVEL PROCESS FOR THE SYNTHESIS OF INDOLINE DERIVATIVES
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Page/Page column 30, (2012/10/18)
The present invention provides an improved process for the synthesis of indoline intermidiate and its pharmaceutically acceptable derivatives, salts or solvates thereof, useful in the synthesis of α-1 adrenoceptor blockers such as silodosin.
