351019-90-4

Basic information

• Product Name: (E)-N-(6-{2-[(N'-tert-butoxycarbonylsulfamoyl)amino]ethoxy}-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl)-2-phenylethenesulfonamide
• Synonyms: (E)-N-(6-{2-[(N'-tert-butoxycarbonylsulfamoyl)amino]ethoxy}-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl)-2-phenylethenesulfonamide
• CAS NO: 351019-90-4
• Molecular Weight: 699.766
• Mol File: 351019-90-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-N-(6-{2-[(N'-tert-butoxycarbonylsulfamoyl)amino]ethoxy}-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl)-2-phenylethenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-N-(6-{2-[(N'-tert-butoxycarbonylsulfamoyl)amino]ethoxy}-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl)-2-phenylethenesulfonamide(351019-90-4)
• EPA Substance Registry System: (E)-N-(6-{2-[(N'-tert-butoxycarbonylsulfamoyl)amino]ethoxy}-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl)-2-phenylethenesulfonamide(351019-90-4)

Safety Data

• Hazardous Substances Data: 351019-90-4(Hazardous Substances Data)

Upstream product

• 147000-89-3 N-tert-butyloxycarbonylsulfamoyl chloride 
• 351019-53-9 (E)-2-Phenyl-ethenesulfonic acid [6-(2-amino-ethoxy)-5-(2-methoxy-phenoxy)-[2,2']bipyrimidinyl-4-yl]-amide 
• 64984-09-4 (E)-(2-phenylethenyl)sulfonamide 
• 150728-13-5 4,6-dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine 
• 351019-39-1 N-[6-Chloro-5-(2-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]-2-phenylethenesulfonamide 

Relevant articles and documents

Ethenesulfonamide derivatives, a novel class of orally active endothelin-A receptor antagonists

In the present article we wish to report the discovery of a novel class of ETA-selective endothelin (ET), receptor antagonists through the modification of the ETA/ETB non-selective antagonist, Ro47-0203 (Bosentan, 1). Repl