35112-27-7

Basic information

• Product Name: ETHYL 2,5-DICHLOROBENZOATE
• Synonyms: ETHYL 2,5-DICHLOROBENZOATE;2,5-DICHLOROBENZOIC ACID ETHYL ESTER;RARECHEM AL BI 0427;Ethyl 2,5-dichlorobenzoate, 98+%;2,5-DICHLOROBENZOIC ACID ETHYL ESTER 97+%;Benzoic acid, 2,5-dichloro-, ethyl ester;LABOTEST-BB LT00454292
• CAS NO: 35112-27-7
• Molecular Formula: C₉H₈Cl₂O₂
• Molecular Weight: 219.06
• EINECS: 252-373-6
• Product Categories: Aromatic Esters;Benzoic acid;Acids & Esters;Chlorine Compounds
• Mol File: 35112-27-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 270-271°C
• Flash Point: 270-271°C
• Appearance: /
• Density: 1.31
• Vapor Pressure: 0.00357mmHg at 25°C
• Refractive Index: 1.5360
• Storage Temp.: Sealed in dry,Room Temperature
• BRN: 2614480
• CAS DataBase Reference: ETHYL 2,5-DICHLOROBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2,5-DICHLOROBENZOATE(35112-27-7)
• EPA Substance Registry System: ETHYL 2,5-DICHLOROBENZOATE(35112-27-7)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39-60-37
• Hazardous Substances Data: 35112-27-7(Hazardous Substances Data)

Usage

General Description

Ethyl 2,5-dichlorobenzoate is a chemical compound used in the production of various consumer products, including insecticides, perfumes, and pharmaceuticals. It is derived from benzoic acid and ethyl alcohol and is characterized by its clear, colorless appearance. Ethyl 2,5-dichlorobenzoate has a strong, sweet odor and is highly soluble in organic solvents. It is commonly used as an intermediate in the manufacturing of other chemicals and is known for its potential as a skin irritant and respiratory toxin if inhaled in high concentrations. Additionally, it is known for its low toxicity to aquatic organisms in environmental applications.

InChI:InChI=1/C9H8Cl2O2/c1-2-13-9(12)7-5-6(10)3-4-8(7)11/h3-5H,2H2,1H3

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 1128-76-3 3-chloro-benzoic acid ethyl ester 

Downstream Products

• 108463-13-4 1-(2,5-Dichlorophenyl)-3-(1,2,3,4-tetrahydro-1-oxo-2-naphthalenyl)-1,3-propanedione 
• 108463-14-5 1-(5-Chloro-2-ethoxyphenyl)-3-(1,2,3,4-tetrahydro-1-oxo-2-naphthalenyl)-1,3-propanedione 
• 108463-23-6 2-(2,5-Dichlorophenyl)-5,6-dihydro-4H-naphtho<1,2-b>pyran-4-one 
• 108463-25-8 2-(5-Chloro-2-ethoxyphenyl)-5,6-dihydro-4H-naphtho<1,2-b>pyran-4-one 
• 56719-08-5 2,5-Dichlorobenzoylacetonitrile 
• 127510-90-1 5-chloro-2-cyano-benzoic acid ethyl ester 
• 23269-73-0 5-(2,5-dichloro-phenyl)-[1,3,4]oxadiazole-2-thiol 
• 67487-35-8 2,5-dichlorobenzhydrazide 
• 2905-69-3 methyl 2,5-dichlorobenzoate 
• 203052-07-7 1-(2,5-dichlorophenyl)-1-hydroxy-2-(2-pyridyl)ethylene 

Relevant articles and documents

Directed magnesiation of polyhaloaromatics using the tetramethylpiperidylmagnesium reagents TMP2Mg×2 LiCl and TMPMgCl×LiCl

A convenient and efficient functionalization of polyhaloaromatics via regioselective magnesiation has been developed. Starting from simple, inexpensive but structurally challenging arenes, metallation by magnesium amide bases was achieved under mild conditions. The desired Grignard reagents were stable towards aryne formation, were obtained in good yields within short reaction times and could be reacted with a variety of typical electrophiles, providing attractive, functionalized building blocks in good to excellent yields. As an application we have prepared the antimicrobial natural product 2,6-dichloro-3-phenethylphenol isolated from the New Zealand liverwort Riccardia marginata. This synthesis involves a mixed bimetallic compound prepared via metallation of a phenylboronic acid pinacol ester derivative and subsequent selective cross-coupling. Copyright