35133-59-6

Basic information

• Product Name: 2-(4-benzyl-3,6-dihydropyridin-1(2H)-yl)-1-(4-methoxyphenyl)propan-1-ol
• CAS NO: 35133-59-6
• Molecular Formula: C₂₂H₂₇NO₂
• Molecular Weight: 337.4553
• Mol File: 35133-59-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 491.5°C at 760 mmHg
• Flash Point: 251°C
• Density: 1.116g/cm³
• Vapor Pressure: 1.78E-10mmHg at 25°C
• Refractive Index: 1.589
• CAS DataBase Reference: 2-(4-benzyl-3,6-dihydropyridin-1(2H)-yl)-1-(4-methoxyphenyl)propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-benzyl-3,6-dihydropyridin-1(2H)-yl)-1-(4-methoxyphenyl)propan-1-ol(35133-59-6)
• EPA Substance Registry System: 2-(4-benzyl-3,6-dihydropyridin-1(2H)-yl)-1-(4-methoxyphenyl)propan-1-ol(35133-59-6)

Safety Data

• Hazardous Substances Data: 35133-59-6(Hazardous Substances Data)

Usage

Chemical class

Dihydropyridines

Explanation

The compound belongs to the class of dihydropyridines, which are known for their vasodilatory and calcium channel blocking properties.

Explanation

As a member of the dihydropyridine class, this compound has the potential to relax blood vessels and improve blood flow.
4. Calcium channel blocking properties

Explanation

The compound may interfere with the normal functioning of calcium channels, which can help regulate the contraction and relaxation of heart muscles and blood vessels.
5. Potential use in pharmaceutical synthesis

Explanation

Due to its unique structure and properties, this compound may be used as a building block or intermediate in the development of new pharmaceuticals targeting cardiovascular diseases or other conditions related to calcium channels and vasodilation.
6. Research tool in the study of calcium channels and vasodilation

Explanation

As a compound with known vasodilatory and calcium channel blocking properties, it can be used in research to better understand the mechanisms and potential therapeutic targets in these areas.
7. Dependence on further testing and research

Explanation

The specific properties and potential applications of this compound would need to be confirmed and explored through additional experiments and studies.

Structure

Combination of a dihydropyridine ring, a benzyl group, a methoxyphenyl group, and a propan-1-ol group
3. Vasodilatory properties

Upstream product

• 121-97-1 4-Methoxypropiophenone 
• 100-66-3 methoxybenzene 
• 21086-33-9 2-bromo-1-(4-methoxyphenyl)-1-propanone 
• 1394148-24-3 2-(4-benzyl-5,6-dihydropyridin-1(2H)-yl)-1-(4-methoxyphenyl)propan-1-one hydrochloride 

Relevant articles and documents

Synthesis and antidepressant activity of arylalkanol-piperidine derivatives as triple reuptake inhibitors

A series of arylalkanol-piperidine derivatives was synthesized, and their triple reuptake inhibition and in vivo activities have been evaluated. Among them, compounds 2a, 2j, 2k, 2m and 2n exhibited high potency for 5-HT, NA and DA transporters. Optimized compounds 2j and 2m showed significant reduction of immobility time compared to that of vehicle in the mouse tail suspension test (TST) test at doses ranging from 10 to 50 mg/kg po, and were not generally motor stimulants at 50 mg/kg dose. In addition, compounds 2j and 2m displayed desirable pharmacokinetic properties in SD rats.