351370-99-5

Basic information

• Product Name: 5-BOC-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE
• Synonyms: 5-BOC-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE;5H-Pyrrolo[3,4-c]pyridine-5-carboxylic acid, octahydro-, 1,1-dimethylethyl ester;tert-butyl hexahydro-1H-pyrrolo[3,4-c]pyridine-5(6H)-carboxylate;tert-butyl octahydro-1H-pyrrolo[3,4-c]pyridine-5-carboxylate;Octahydro-pyrrolo[3,4-c]pyridine-5-carboxylic acid tert-butyl ester;tert-Butyl 1,2,3,3a,4,6,7,7a-octahydropyrrolo[3,4-c]pyridine-5-carboxylate;tert-butyl octahydropyrrolo[3,4-c]pyridine-5-carboxylate;5-BOC-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE(Hydrochloride form)
• CAS NO: 351370-99-5
• Molecular Formula: C₁₂H₂₂N₂O₂
• Molecular Weight: 226.32
• Product Categories: pharmacetical
• Mol File: 351370-99-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 313.81 °C at 760 mmHg
• Flash Point: 143.587 °C
• Appearance: /
• Density: 1.053 g/cm³
• Vapor Pressure: 0.000485mmHg at 25°C
• Refractive Index: 1.489
• Storage Temp.: 2-8°C(protect from light)
• PKA: 11.15±0.20(Predicted)
• CAS DataBase Reference: 5-BOC-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BOC-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE(351370-99-5)
• EPA Substance Registry System: 5-BOC-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE(351370-99-5)

Safety Data

• Hazard Codes: N
• Statements: 50
• Safety Statements: 61
• RIDADR: UN3077
• Hazardous Substances Data: 351370-99-5(Hazardous Substances Data)

Usage

General Description

5-BOC-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE is a chemical compound often used in chemical laboratories and in industrial manufacturing. Information about its molecular weight, density, boiling point, flash point, exact mass, PSA, and other similar chemical properties are essential for scientists and researchers. Currently, specific information regarding its uses and hazards are not widely available, indicating it may be a specialized compound used in certain research areas. Generally, chemicals in the pyridine class are known for their use in the synthesis of pharmaceuticals and agrochemicals. However, the specifics of this compound, including its safety profile and hazard information, should be examined in the appropriate Material Safety Data Sheet (MSDS) before handling.

InChI:InChI=1/C12H22N2O2/c1-12(2,3)16-11(15)14-5-4-9-6-13-7-10(9)8-14/h9-10,13H,4-8H2,1-3H3

Upstream product

• 4664-08-8 cinchomeronic anhydride 
• 490-11-9 3,4-pyridinecarboxylic acid 
• 351370-97-3 tert-butyl 2-benzylhexahydro-1H-pyrrolo[3,4-c]pyridine-5(6H)-carboxylate 
• 351370-98-4 2-benzyloctahydro-1H-pyrrolo[3.4-c]pyridine 
• 939793-58-5 2-benzylhexahydro-1H-pyrrolo[3.4-c]pyridine-1,3(2H)-dione 
• 4664-01-1 3,4-pyridinedicarboximide 
• 18205-25-9 2-benzyl-1H-pyrrolo[3,4-c]pyridine-1,3(2H)-dione 

Downstream Products

• 1438083-37-4 tert-butyl 2-(3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)hexahydro-1H-pyrrolo[3,4-c] pyridine-5(6H)-carboxylate 
• 1438073-56-3 N-(3-chloro-4-fluorophenyl)-6-(3-(hexahydro-1H-pyrrolo[3.4-c]pyridin-2(3H)-yl)propoxy)-7-methoxyquinazolin-4-amine 

Relevant articles and documents

ISOQUINOLINESULFONYL DERIVATIVE AS RHO KINASE INHIBITOR

The present invention discloses a class of isoquinolinesulfonyl derivatives as RHO kinase inhibitors, and pharmaceutical compositions thereof, and relates to pharmaceutically acceptable uses thereof. Specifically, the present invention relates to a compound as represented by formula (I), or a pharmaceutically acceptable salt thereof.

AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE

The present invention relates to the field of medicine. Provided herein are aminoquinazoline derivatives, their salts and pharmaceutical formulations useful in modulating the protein tyrosine kinase activity, and in modulating inter-and/or intra-cellular signaling. Also provided herein are pharmaceutically acceptable compositions comprising the aminoquinazoline compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.