35146-32-8Relevant articles and documents
Preparation method of N - 9 - fluorenylmethoxycarbonyl - N ' - trityl - L - histidine
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Paragraph 0012; 0028-0029; 0032-0033, (2021/09/21)
The invention relates to the technical field of medical intermediate synthesis, in particular to a synthetic method of N - 9 - fluorenylmethoxycarbonyl - N ' - trityl - L - histidine, which comprises the following steps: taking L - histidine as a raw material and protecting a - amino groups on histidine by using a silane protective agent. A silane protecting substance Nim - trityl histidine is obtained by reaction with triphenylchloromethane, followed by addition of water to the silane protecting group. The silane protecting substance Nim - trityl histidine is reacted with 9 - fluorenylmethoxycarbonyl protecting reagent to give the target product N - 9 - fluorenylmethoxycarbonyl - N ' - trityl - L - histidine. The N - 9 -fluorenylmethoxycarbonyl - N ' - trityl - L - histidine preparation method provided by the invention is simple and convenient to operate, high in yield and low in comprehensive production cost, and is suitable for industrial large-scale production.
Self-healing response in supramolecular polymers based on reversible zinc-histidine interactions
Enke, Marcel,Bode, Stefan,Vitz, Jürgen,Schacher, Felix H.,Harrington, Matthew J.,Hager, Martin D.,Schubert, Ulrich S.
, p. 274 - 282 (2015/07/01)
Histidine-metal interactions are utilized in many biological materials as reinforcing crosslinks, and in particular, are believed to contribute as reversible crosslinks to the intrinsic self-recovery behavior of mussel byssal threads. In this contribution
DIARYLSULPHID BACKBONE CONTAINING PHOTOLABILE PROTECTING GROUPS
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Page/Page column 42-43, (2012/10/18)
The present invention relates to photoactivable protecting groups containing a diarylsulphid chromophore, a method for the synthesis thereof and their use as photoactivable protecting groups using maskless photolithography based array synthesis. wherein R2 is [Formula II] or wherein R2 is [Formula III] or [Formula IV] wherein R7 is a natural amino acid, a non-natural amino acid or an amino acid derivative forming an urethan bond to formula Ib, or wherein formula IV represents the carboxy function of a natural amino acid, a non-natural amino acid or an amino acid derivative, forming an ester bond to formula Ib.