351529-73-2Relevant articles and documents
Synthesis and antibacterial activity of novel 4-pyrrolidinylthio carbapenems. Part IV. 2-Alkyl substituents containing cationic heteroaromatics linked via a C-C bond
Azami, Hidenori,Barrett, David,Tanaka, Akira,Sasaki, Hiroshi,Matsuda, Keiji,Sakurai, Minoru,Terasawa, Takeshi,Shirai, Fumiyuki,Chiba, Toshiyuki,Matsumoto, Yoshimi,Tawara, Shuichi
, p. 961 - 982 (2001)
The synthesis and biological activity of a novel series of 2-alkyl-4-pyrrolidinylthio-β-methylcarbapenems containing a variety of cationic heteroaromatic substituents linked via a C-C bond is described. As a result of these studies, we selected FR21818 (1
Substituted 3-pyrrolidinylthio-carbapenems as antimicrobial agents
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, (2008/06/13)
A compound of the formula: STR1 in which R1 is carboxy or protected carboxy, R2 is 1-hydroxyethyl, R3 is methyl, R4 is optionally substituted pyridyl(lower)alkyl, optionally N-substituted 2-oxopiperazin-1-yl-(lo